Evidence map›Paper›PMID 30333120›Full record

ArticleBlood2019

Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells.

Stéphanie Humblet-Baron, John S Barber, Carlos P Roca, Aurelie Lenaerts, Pandelakis A Koni, Adrian Liston

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Monocyte Involvement in the Pathogenesis of Myeloproliferative Neoplasms.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Anti-Interferon-γ Therapy for Cytokine Storm Syndromes.Advances in experimental medicine and biology · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Stéphanie Humblet-BaronVlaams Instituut voor Biotechnologie Center for Brain and Disease Research, Leuven, Belgium.ORCID 0000-0003-4684-069X
John S BarberVlaams Instituut voor Biotechnologie Center for Brain and Disease Research, Leuven, Belgium.
Carlos P RocaVlaams Instituut voor Biotechnologie Center for Brain and Disease Research, Leuven, Belgium.ORCID 0000-0003-0230-1926
Aurelie LenaertsVlaams Instituut voor Biotechnologie Center for Brain and Disease Research, Leuven, Belgium.
Pandelakis A KoniGeorgia Cancer Center, Augusta University, Augusta, GA.
Adrian ListonVlaams Instituut voor Biotechnologie Center for Brain and Disease Research, Leuven, Belgium.ORCID 0000-0002-6272-4085
Vlaams Instituut voor Biotechnologie · BEAugusta University Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) are a key cell type in the initiation of the adaptive immune response. Recently, an additional role for DCs in suppressing myeloproliferation was discovered. Myeloproliferative disorder (MPD) was observed in murine studies with constitutive depletion of DCs, as well as in patients with congenital deficiency in DCs caused by mutations in

Indexed as

Cell CommunicationAnimalsCD11c AntigenCD4-Positive T-LymphocytesDendritic CellsLymphocyte ActivationMice, Inbred C57BLMyeloid CellsMyeloproliferative DisordersCD11c Antigen

Identifiers

PMID30333120
PMCPMC6356150
OpenAlexW2897105268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.