Evidence map›Paper›PMID 30333008›Full record

ReviewBMC infectious diseases2018

A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature.

Joseph M Yabes, Serafim Perdikis, David B Graham, Ana Markelz

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A Rare Case of Infective Endocarditis Caused byJournal of community hospital internal medicine perspectives · 2025
    Article
  5. Emerging pathogensFuture microbiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Journal of medical cases · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Microbiome Analysis Reveals the Attenuation Effect ofFrontiers in cellular and infection microbiology · 2020
    Article
  17. An interesting case of pacemaker endocarditis.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph M YabesBrooke Army Medical Center, Department of Infectious Disease, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, San Antonio, TX, 78234, USA. joseph.m.yabes2.mil@mail.mil.ORCID http://orcid.org/0000-0002-8119-5510
Serafim PerdikisBrooke Army Medical Center, Department of Internal Medicine, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, San Antonio, TX, 78234, USA.
David B GrahamBrooke Army Medical Center, Department of Cardiothoracic Surgery, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, San Antonio, TX, 78234, USA.
Ana MarkelzBrooke Army Medical Center, Department of Infectious Disease, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, San Antonio, TX, 78234, USA.
Brooke Army Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAerococcus urinae is a gram-positive, alpha-hemolytic coccus bacterium primarily implicated in less than 1 % of all symptomatic urinary tract infections. Risk factors for disease include male gender, advanced age, and comorbid genitourinary tract pathology. Infections beyond the genitourinary tract are rare, though spondylodiscitis, perineal abscesses, lymphadenitis, bacteremia, meningitis, and endocarditis have been reported. Less than fifty cases of A. urinae infective endocarditis (IE) have been described in the literature. The rare occurrence of A. urinae in human infections and resultant lack of randomized controlled trials have resulted in a significant degree of clinical uncertainty in the management of A. urinae IE. CASE PRESENTATION: We present an unusual case of a forty-three year-old male with A. urinae infective endocarditis (IE) who was successfully treated with mitral valve replacement and six weeks of penicillin/gentamicin therapy. In addition, we include a comprehensive review of all reported cases of IE due to A. urinae with specific attention to therapeutic regimens and treatment durations.

conclusionRecent advances in diagnostic technology have led to an increase in the frequency A. urinae is diagnosed. Reviewing cases of Aerococcus urinae infections, their clinical courses and subsequent management can assist future healthcare providers and their patients.

Indexed as

AdultAerococcusAnti-Bacterial AgentsComorbidityEndocarditis, BacterialGram-Positive Bacterial InfectionsHumansMaleMitral ValveSurvival AnalysisAnti-Bacterial AgentsAerococciAerococcus urinaeInfective endocarditis

Identifiers

PMID30333008
PMCPMC6191913
OpenAlexW2895946421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.