Evidence map›Paper›PMID 30333004›Full record

Trial reportBMC psychiatry2018

B-positive: a randomized controlled trial of a multicomponent positive psychology intervention for euthymic patients with bipolar disorder - study protocol and intervention development.

Jannis T Kraiss, Peter M Ten Klooster, Melissa Chrispijn, Hester R Trompetter, Anja W M M Stevens, Erica Neutel, Ralph W Kupka, Ernst T Bohlmeijer

Abstract readMulticenter StudyPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jannis T KraissCenter for eHealth and Well-being Research, Department of Psychology, Health, and Technology, University of Twente, PO Box 217, Enschede, 7500 AE, the Netherlands. j.t.kraiss@utwente.nl.ORCID 0000-0002-5342-3029
Peter M Ten KloosterCenter for eHealth and Well-being Research, Department of Psychology, Health, and Technology, University of Twente, PO Box 217, Enschede, 7500 AE, the Netherlands.
Melissa ChrispijnSpecialized Center for Bipolar Disorders, Dimence group, Pikeursbaan 3, Deventer, 7411 GT, the Netherlands.
Hester R TrompetterCenter of Research on Psychological and Somatic Disorders, TS Social and Behavioral Sciences, Tilburg University, PO Box 90153, Tilburg, 5000 LE, the Netherlands.
Anja W M M StevensSpecialized Center for Bipolar Disorders, Dimence group, Pikeursbaan 3, Deventer, 7411 GT, the Netherlands.
Erica NeutelDutch Association for Manic Depressives and Relatives, Stationsplein 125, Amersfoort, 3818 LE, the Netherlands.
Ralph W KupkaDepartment of Psychiatry, VU University Medical Center, Oldenaller 1, Amsterdam, 1081 HJ, the Netherlands.
Ernst T BohlmeijerCenter for eHealth and Well-being Research, Department of Psychology, Health, and Technology, University of Twente, PO Box 217, Enschede, 7500 AE, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBipolar disorder (BD) is characterized by recurrent (hypo)manic and depressive episodes, alternating with euthymic states in which patients are relatively symptom free. Besides clinical recovery, it is important to also strive for improvement of mental well-being and personal recovery. One prominent field focussing on the improvement of well-being is positive psychology. However, studies assessing the effects of positive psychology or personal recovery interventions for people with BD are scarce and have used weak methodological designs. The study described in this protocol article aims to assess the effectiveness of a multicomponent positive psychology intervention ("Living well with bipolar disorder") adjusted for people with BD in the euthymic phase to improve well-being and personal recovery.

methodThe study concerns a pragmatic randomized multicenter trial. The principle objective of the study is to assess whether the positive psychology intervention offered to BD patients in remission in addition to usual care (CAU) is more effective than CAU. The study will include 112 participants randomized to either the experimental condition receiving the intervention in addition to CAU or the control condition receiving CAU. The study population are patients with BD I or II in the euthymic phase. The inclusion criteria are 1) diagnosis of BD I or BD II, 2) between the ages of 18-65, 3) four or more supportive sessions in the last year, and 4) only residual depressive or manic symptoms. Patients are excluded if they are in a depressive or manic episode, have current addiction problems or have optimal levels of well-being. Measurements take place at baseline, post-intervention and follow-up 6 and 12 months from baseline. Outcomes of measures include positive well-being, personal recovery, psychopathology, self-compassion, positive relationships, dampening of positive affect and relapse. DISCUSSION: The outlined study will be the first RCT examining the effects of a multicomponent positive psychology intervention for patients with bipolar disorder. Several limitations, including generalizability of the results and possible attrition issues, are discussed in advance.

trial registrationThis study has been registered in the Netherlands Trial Register ( NTR6729 ) on 12 October 2017.

Indexed as

AdolescentAdultAgedBipolar DisorderEarly Medical InterventionEmpathyFemaleFollow-Up StudiesHumansMaleMental HealthMiddle AgedNetherlandsOptimismYoung AdultBipolar disorderEffectEffectivenessFlourishingInterventionPersonal recoveryPositive psychologyRandomized controlled trialRCTWell-being

Identifiers

PMID30333004
PMCPMC6192172

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.