Evidence map›Paper›PMID 30332998›Full record

ArticleBMC cancer2018

Bioelectrical impedance analysis for monitoring cancer patients receiving chemotherapy and home parenteral nutrition.

Paolo Cotogni, Taira Monge, Maurizio Fadda, Antonella De Francesco

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06429189 (An Online Home-based Combined Exercise Intervention With Self-selected Intensity for Women With Breast Cancer), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06429189 naunknown statusnot on this mapstarted 2024, after this paper: background citation

An Online Home-based Combined Exercise Intervention With Self-selected Intensity for Women With Breast Cancer: The Home-Combo Randomized Controlled Trial.

TypeinterventionalSponsorGrupo LusófonaRan2024 to 2025Enrolled98ConditionsBreast Cancer, Chemotherapy EffectArmsHome-based combined exercise program with self-selected intensity
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. High-protein home parenteral nutrition in malnourished oncology patients: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  2. Trial
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  6. Review
  7. Observational
  8. Effect of a 12-week exercise program on phase angle in women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  9. Article
  10. Review
  11. Review
  12. SINPE Position Paper on the use of home parenteral nutrition in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Review
  13. Supplemental parenteral nutrition in cancer care: why, who, when.Therapeutic advances in medical oncology · 2022
    Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paolo CotogniDepartment of Anaesthesia and Intensive Care, Pain Management and Palliative Care, S. Giovanni Battista Hospital, University of Turin, C.so Bramante 88, 10126, Turin, Italy. paolo.cotogni@unito.it.ORCID http://orcid.org/0000-0002-4930-8984
Taira MongeUnit of Parenteral Nutrition in Oncology, S. Giovanni Battista Hospital, C.so Bramante 88, 10126, Turin, Italy.
Maurizio FaddaClinical Nutrition, S. Giovanni Battista Hospital, C.so Bramante 88, 10126, Turin, Italy.
Antonella De FrancescoClinical Nutrition, S. Giovanni Battista Hospital, C.so Bramante 88, 10126, Turin, Italy.
Azienda Ospedaliero Universitaria San Giovanni Battista · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHome parenteral nutrition (HPN) can improve survival, quality of life, nutritional and functional status in cancer patients. Bioelectrical impedance analysis (BIA) is a non-invasive, validated method to assess body composition. The objective of this prospective single-arm study was to investigate the impact of HPN in advanced cancer patients receiving chemotherapy assessed by BIA, clinical and laboratory measures.

methodsAdult malnourished cancer outpatients with solid tumors receiving anticancer treatments who were candidates for daily HPN were enrolled. Patients were assessed at baseline (T0), 60 (T1) and 90 days (T2) after HPN start. Assessments included anthropometric and clinical-oncological characteristics, performance status, inflammatory response and Patient-Generated Subjective Global Assessment (PG-SGA).

resultsSixty-five advanced cancer patients were enrolled. Median overall survival was 317 days. Body weight, BMI, oral calorie and protein intake increased over time (P < 0.01). At T2 the proportion of well-nourished patients, Karnofsky performance status and modified Glasgow prognostic score were improved (P < 0.01), total body water was reduced (P = 0.04), and fat mass increased (P = 0.04). Reactance, resistance and phase angle were significantly associated with survival at T0, T1, and T2, respectively. At T2, PG-SGA category A was a predictor of survival (P < 0.0001).

conclusionsAfter 90 days of HPN, patients experienced significantly improved nutritional status, performance status, prognostic score and some BIA measures. HPN may be an important therapy in oncology patients receiving chemotherapy. Longitudinal use of BIA may help track the effects of HPN and disease progression, potentially contributing to optimal global patient management.

Indexed as

Electric ImpedanceAdultAgedAntineoplastic AgentsBody CompositionDrug MonitoringFemaleHumansLongitudinal StudiesMaleMiddle AgedNeoplasmsNutritional StatusParenteral Nutrition, HomeSurvival RateAntineoplastic AgentsBioelectrical impedance analysisBody compositionCancerHome parenteral nutritionMalnutrition

Identifiers

PMID30332998
PMCPMC6192128
OpenAlexW2897241084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.