Evidence map›Paper›PMID 30332851›Full record

ArticleMarine drugs2018

Sandensolide Induces Oxidative Stress-Mediated Apoptosis in Oral Cancer Cells and in Zebrafish Xenograft Model.

Chung-I Yu, Chung-Yi Chen, Wangta Liu, Po-Chih Chang, Chiung-Wei Huang, Kuang-Fen Han, In-Pin Lin, Mei-Ying Lin, Chien-Hsing Lee

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Zebrafish live imaging: a strong weapon in anticancer drug discovery and development.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
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  8. Zebrafish as a Model for Anticancer Nanomedicine Studies.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Chung-I YuDepartment of Orthopedics, Chi Mei Medical Center, Liouying, Tainan 73659, Taiwan. tlig9212148@gmail.com.
Chung-Yi ChenDepartment of Nutrition and Health Science, School of Medical and Health Sciences, Fooyin University, Kaohsiung 83102, Taiwan. xx377@fy.edu.tw.ORCID 0000-0002-7026-3944
Wangta LiuDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. liuwangta@kmu.edu.tw.
Po-Chih ChangDivision of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan. dr.changpochih@hotmail.com.
Chiung-Wei HuangDepartment of Physiology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. g10054b@ms51.hinet.net.
Kuang-Fen HanDepartment of Nursing, Min-Hwei Junior College of Health Care Management, Tainan City 73658, Taiwan. kfhan@mail.mhchcm.edu.tw.
In-Pin LinDepartment of Pharmacology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. inpin71126@msn.com.
Mei-Ying LinCancer Center, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan. a0922063039@gmail.com.
Chien-Hsing LeeDepartment of Pharmacology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. chlee0818@gmail.com.
Kaohsiung Medical University · TWChi Mei Medical Center · TWFooyin University · TWMin-Hwei College of Health Care Management · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presently, natural sources and herbs are being sought for the treatment of human oral squamous cell carcinoma (OSCC) in order to alleviate the side effects of chemotherapy. This study investigates the effect of sandensolide, a cembrane isolated from

Indexed as

AnthozoaAcetylcysteineAnimalsAntineoplastic AgentsApoptosisCarcinoma, Squamous CellCell Cycle CheckpointsCell Line, TumorCell ProliferationDiterpenesHumansMouth NeoplasmsOxidative StressReactive Oxygen SpeciesXenograft Model Antitumor AssaysZebrafishAcetylcysteineAntineoplastic AgentscembraneDiterpenesReactive Oxygen Speciessandensolidehuman oral squamous cell carcinomareactive oxygen speciessandensolide

Identifiers

PMID30332851
PMCPMC6213332
OpenAlexW2897743613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.