ArticleInternational journal of environmental research and public health2018
Association between Dry Eye Disease, Air Pollution and Weather Changes in Taiwan.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Applications of topical immunomodulators enhance clinical signs of vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC): a meta-analysis.International ophthalmology · 2024Pooled it
- Chronic ambient air pollution and the incidence of blepharitis and blepharoconjunctivitis: a nationwide population-based cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Environmental Triggers and Ocular Disease Networks: Analyzing the Impact of Air Pollutants and Meteorological Factors Using Fuzzy Cognitive Maps.Environment & health (Washington, D.C.) · 2026Article
- Environmental Drivers of Dry Eye Disease: A Narrative Review of Pollutants, Climate, and Indoor Exposures with Practice Recommendations.Ophthalmology and therapy · 2026Review
- The Immunopathogenesis of uveitis.Frontiers in medicine · 2026Review
- Models Estimating the Effects of Changes in the Concentration of Specific Climatic Pollutants and Temperature on the Prevalence of Acute Ophthalmic Inflammatory Conditions: A Retrospective Cross-Sectional Observational Study.Journal of ophthalmology · 2026Article
- Association between dry eye disease and temperature is modified by residential greenness: case-crossover study in Beijing, China.BMC public health · 2025Article
- Big Data on Climatic and Environmental Parameters Associated with Acute Ocular Surface Symptoms and Therapeutic Assessment: Eye Drops Sales, Google Trends and Environmental Changes.Vision (Basel, Switzerland) · 2025Article
- Public Interest in Dry Eye Disease and Its Association With Environmental Parameters in Taiwan: Google Trends Infodemiology Study.JMIR infodemiology · 2025Article
- Polyphenol-Loaded Nanodevices as Innovative Therapeutic Strategies for Dry Eye Disease: Advances and Perspectives.Antioxidants (Basel, Switzerland) · 2025Review
- Delayed effects of the relative humidity on the outpatient visits of dry eye disease in Shanghai, China: effect modification by green and blue space.Journal of global health · 2025Article
- Source-specific fine particulates emission linked to prevalence of ophthalmic cases in India.Scientific reports · 2025Observational
- Associations between air pollution and daily outpatient visits for dry eye disease and the effect modification of temperature.BMC public health · 2025Article
- Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study.Scientific reports · 2025Article
- Association between traffic-related air pollution and risk of outpatient visits for dry eye disease in a megacity along the subtropical coast in South China.BMC public health · 2025Article
- Adverse effects of meteorological factors and air pollutants on dry eye disease: a hospital-based retrospective cohort study.Scientific reports · 2024Article
- One Soul and Several Faces of Evaporative Dry Eye Disease.Journal of clinical medicine · 2024Review
- Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China.Frontiers in public health · 2024Article
- A Comprehensive Analysis of the Influence of Temperature and Humidity on Dry Eye Disease.Korean journal of ophthalmology : KJO · 2023Article
- Medicine versus environmental manipulations as approaches to treating dry eye disease: why does medicine usually win?BMJ open ophthalmology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dry eye disease (DED) has become a common eye disease in recent years and appears to be influenced by environmental factors. This study aimed to examine the association between the first occurrence of DED, air pollution and weather changes in Taiwan. We used the systematic sampling cohort database containing 1,000,000 insureds of the National Health Insurance of Taiwan from 2004 to 2013, and identified a total of 25,818 eligible DED subjects. Environmental data, including those of air pollutants, temperature and relative humidity, were retrieved from the environmental monitoring stations adjacent to subjects' locations of clinics as exposure information. We applied the case-crossover design, which used the same subjects experiencing exposures on diagnosis days as cases and those on other days as controls. The descriptive statistics showed that the first occurrences of DED were the most for the elderly by age (53.6%), women by gender (68.9%), and spring by season (25.9%). Multivariate conditional logistic regression analyses indicated that carbon monoxide (CO), nitrogen dioxide (NO₂), and temperature were positively associated with DED (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.