Evidence map›Paper›PMID 30332776›Full record

ArticleHigh-throughput2018

Development and Assessment of a Diagnostic DNA Oligonucleotide Microarray for Detection and Typing of Meningitis-Associated Bacterial Species.

Stephanie A Bannister, Stephen P Kidd, Elizabeth Kirby, Sonal Shah, Anvy Thomas, Richard Vipond, Michael J Elmore, Andrew Telfer Brunton, Peter Marsh, Steve Green and 2 more

Open access · goldAbstract read
In one paragraph

Article in High-throughput, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Stephanie A BannisterPublic Health England, Porton Down, Salisbury SP4 0JG, UK. karen.kempsell@phe.gov.uk.
Stephen P KiddPublic Health England, Porton Down, Salisbury SP4 0JG, UK. Stephen.Kidd@hhft.nhs.uk.
Elizabeth KirbyPublic Health England, Porton Down, Salisbury SP4 0JG, UK. lizkirby2001@yahoo.co.uk.
Sonal ShahPublic Health England, Porton Down, Salisbury SP4 0JG, UK. sonal.shah@lshtm.ac.uk.
Anvy ThomasPublic Health England, Porton Down, Salisbury SP4 0JG, UK. Anvy.Thomas@phe.gov.uk.
Richard VipondPublic Health England, Porton Down, Salisbury SP4 0JG, UK. Richard.Vipond@phe.gov.uk.
Michael J ElmorePublic Health England, Porton Down, Salisbury SP4 0JG, UK. Mike.Elmore@phe.gov.uk.
Andrew Telfer BruntonDepartment of Clinical Microbiology, Royal Cornwall Hospitals NHS Trust, Penventinnie Lane, Treliske, Truro, Cornwall TR1 3LQ, UK. latbex2@hotmail.com.
Peter MarshPublic Health England Laboratory Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK. Peter.Marsh@phe.gov.uk.
Steve GreenPublic Health England Laboratory Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK. Steve.Green@phe.gov.uk.
Nigel J SilmanPublic Health England, Porton Down, Salisbury SP4 0JG, UK. Nigel.Silman@phe.gov.uk.
Karen E KempsellPublic Health England, Porton Down, Salisbury SP4 0JG, UK. karen.kempsell@phe.gov.uk.ORCID 0000-0002-3059-9718
Public Health England · GBSouthampton General Hospital · GBRoyal Cornwall Hospital Trust · GB

Funding

Public Health England Pipeline Fund 107686
6 · The paper itself

Abstract

Meningitis is commonly caused by infection with a variety of bacterial or viral pathogens. Acute bacterial meningitis (ABM) can cause severe disease, which can progress rapidly to a critical life-threatening condition. Rapid diagnosis of ABM is critical, as this is most commonly associated with severe sequelae with associated high mortality and morbidity rates compared to viral meningitis, which is less severe and self-limiting. We have designed a microarray for detection and diagnosis of ABM. This has been validated using randomly amplified DNA targets (RADT), comparing buffers with or without formamide, in glass slide format or on the Alere ArrayTube

Indexed as

ArrayTubeassaybacterialdiagnosisdiagnosticinfectionmeningitismicroarray

Identifiers

PMID30332776
PMCPMC6306750
OpenAlexW2897697160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.