Evidence map›Paper›PMID 30332739›Full record

ArticleInternational journal of molecular sciences2018

Novel C15 Triene Triazole, D-A Derivatives Anti-HepG2, and as HDAC2 Inhibitors: A Synergy Study.

Zhiwen Qi, Chengzhang Wang, Jianxin Jiang, Caie Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Zhiwen QiInstitute of Chemical Industry of Forest Products, China Academy of Forestry, Nanjing 210042, China. angelkissgod@163.com.ORCID 0000-0002-0679-7837
Chengzhang WangInstitute of Chemical Industry of Forest Products, China Academy of Forestry, Nanjing 210042, China. wangcz@icifp.cn.
Jianxin JiangCollege of Material Science and Technology, Beijing Forestry University, Beijing 100083, China. jiangjx@bjfu.edu.cn.
Caie WuCollege of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210000, China. wucaie@njfu.edu.cn.
Beijing Forestry University · CNInstitute of Chemical Industry of Forest Products · CNNanjing Forestry University · CN

Funding

Jiangsu Provincial Key Laboratory of Biomass Energy and Materials Basic Research Business Project JSBEM-S-201509National Natural Science Foundation of China 31570564
6 · The paper itself

Abstract

A series of novel C15 urushiol derivatives were designed by introducing a pechmann structure and F-, Cl-, and Br-nitro substituents with different electronic properties into its alkyl side chain, as well as a triazolyl functional group in its aromatic oxide. Their chemical structures were determined based on the analysis of the NMR (nuclear magnetic resonance) spectroscopic and mass spectrometric data. The results showed that compound

Indexed as

Antineoplastic AgentsApoptosisCalciumCatecholsDrug SynergismHep G2 CellsHistone Deacetylase InhibitorsHumansInhibitory Concentration 50IonsLigandsMembrane Potential, MitochondrialMolecular Docking SimulationTriazolesAntineoplastic AgentsCalciumCatecholsHistone Deacetylase InhibitorsIonsLigandsTriazolesurushiolanti-tumordiels-alderHDAC2pechmanntriazoleurushiol

Identifiers

PMID30332739
PMCPMC6214004
OpenAlexW2897385892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.