Evidence map›Paper›PMID 30332625›Full record

ArticleImmunity2018

Lineage Specifiers in Lung Cancer Are Ahead of Their TIME.

Kelli A Connolly, Brittany Fitzgerald, Nikhil S Joshi

Abstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kelli A ConnollyYale University School of Medicine, Department of Immunobiology, New Haven, CT 06519, USA.
Brittany FitzgeraldYale University School of Medicine, Department of Immunobiology, New Haven, CT 06519, USA.
Nikhil S JoshiYale University School of Medicine, Department of Immunobiology, New Haven, CT 06519, USA. Electronic address: nikhil.joshi@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The factors that shape the distinctive tumor-immune landscapes of various types and subtypes of cancer remain poorly understood. In this issue of Immunity, Mollaoglu et al. (2018) reveal a mechanistic link between the function of lineage specifiers SOX2 and NKX2-1 and the presence of neutrophils in the tumor-immune microenvironment of lung cancer.

Indexed as

Lung NeoplasmsCell DifferentiationHumansSOXB1 Transcription FactorsTumor MicroenvironmentSOX2 protein, humanSOXB1 Transcription Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.