ArticleThe New England journal of medicine2018
Should Aspirin Be Used for Primary Prevention in the Post-Statin Era?
Article in The New England journal of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2019Guideline
- Aspirin Efficacy in Primary Prevention: A Meta-analysis of Randomized Controlled Trials.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019Pooled it
- Polygenic risk, aspirin, and primary prevention of coronary artery disease.European heart journal. Cardiovascular pharmacotherapy · 2025Trial
- Aspirin and omega-3 fatty acid status interact in the prevention of cardiovascular diseases in Framingham Heart Study.Prostaglandins, leukotrienes, and essential fatty acids · 2021Trial
- Association of Statin Use With Disability-Free Survival and Cardiovascular Disease Among Healthy Older Adults.Journal of the American College of Cardiology · 2020Trial
- Trial
- Cardiovascular disease and cardiovascular pharmacotherapy: the challenges and the research continue.European heart journal. Cardiovascular pharmacotherapy · 2025Article
- A survey of internists' recommendations for aspirin in older adults and barriers to evidence-based use.Journal of thrombosis and thrombolysis · 2022Article
- Examining evidence of time-dependent treatment effects: an illustration using regression methods.Trials · 2022Article
- Implications of the heterogeneity between guideline recommendations for the use of low dose aspirin in primary prevention of cardiovascular disease.American journal of preventive cardiology · 2022Review
- Analysis of Aspirin Use and Cardiovascular Events and Mortality Among Adults With Hypertension and Controlled Systolic Blood Pressure.JAMA network open · 2022Article
- Can low-dose aspirin help the RECOVERY of patients hospitalized with COVID-19?European heart journal · 2022Article
- Aspirin for Primary Stroke Prevention; Evidence for a Differential Effect in Men and Women.Frontiers in neurology · 2022Review
- Relation of Pre-Stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes.Annals of neurology · 2021Article
- Aspirin, Statins, and Primary Prevention: Opportunities for Shared Decision Making in the Face of Uncertainty.Current cardiology reports · 2021Review
- Aspirin Use and Misuse for the Primary Prevention of Cardiovascular Diseases.American journal of preventive medicine · 2021Article
- The ASPREE Trial: An Unanticipated Stimulus for Greater Precision in Prevention?Journal of the National Cancer Institute · 2021Article
- Aspirin in the Modern Era of Cardiovascular Disease Prevention.Methodist DeBakey cardiovascular journal · 2021Review
- Misuse of Aspirin and Associated Factors for the Primary Prevention of Cardiovascular Disease.Frontiers in cardiovascular medicine · 2021Article
- Inflammatory Cytokines and Atherosclerotic Plaque Progression. Therapeutic Implications.Current atherosclerosis reports · 2020Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
30332575What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.