ArticleAngewandte Chemie (International ed. in English)2019
Chemoselective α,β-Dehydrogenation of Saturated Amides.
Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Recent advances in piperine and its derivatives as potential anticancer agents.RSC medicinal chemistry · 2026Review
- Site-Selective Benzylic Dehydrogenation of Alkylindoles.JACS Au · 2025Article
- Synthesis of Chiral Carbocycles via Enantioselective β,γ-Dehydrogenation.Nature synthesis · 2024Article
- Accessing Z-Enynes via Cobalt-Catalyzed Propargylic Dehydrogenation.Angewandte Chemie (International ed. in English) · 2024Article
- A facile synthesis of α,β-unsaturated imines via palladium-catalyzed dehydrogenation.Nature communications · 2024Article
- Comprehensive Mechanistic Analysis of Palladium- and Nickel-Catalyzed α,β-Dehydrogenation of Carbonyls via Organozinc Intermediates.The Journal of organic chemistry · 2024Article
- Synthesis of 1,3-Dienes via Ligand-Enabled Sequential Dehydrogenation of Aliphatic Acids.Journal of the American Chemical Society · 2023Article
- Challenges and Breakthroughs in Selective Amide Activation.Angewandte Chemie (International ed. in English) · 2022Review
- Challenges and Breakthroughs in Selective Amide Activation.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022Review
- Multiple remote C(spChemical science · 2022Article
- Selective desaturation of amides: a direct approach to enamides.Chemical science · 2022Article
- Cobalt-catalyzed chemoselective dehydrogenation through radical translocation under visible light.Chemical science · 2022Article
- Direct synthesis ofiScience · 2021Article
- Seleninic Acid Potassium Salts as Water-Soluble Biocatalysts with Enhanced Bioavailability.Materials (Basel, Switzerland) · 2020Article
- Chemoselective formal β-functionalization of substituted aliphatic amides enabled by a facile stereoselective oxidation event.Chemical science · 2019Article
- A Mild Synthesis of Bicyclic Alkoxyoxazolium Salts from Proline and Pipecolic Acid Derivatives.European journal of organic chemistry · 2019Article
- Copper-catalyzed dehydrogenative γ-C(spNature communications · 2019Article
- Chemoselective α,β-Dehydrogenation of Saturated Amides.Angewandte Chemie (International ed. in English) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We report a method for the selective α,β-dehydrogenation of amides in the presence of other carbonyl moieties under mild conditions. Our strategy relies on electrophilic activation coupled to in situ selective selenium-mediated dehydrogenation. The α,β-unsaturated products were obtained in moderate to excellent yields, and their synthetic versatility was demonstrated by a range of transformations. Mechanistic experiments suggest formation of an electrophilic Se
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.