Evidence map›Paper›PMID 30332517›Full record

ArticleJournal of surgical oncology2018

Comparison of gastric cancer survival after R0 resection in the US and China.

Ping Li, Chang-Ming Huang, Chao-Hui Zheng, Ashley Russo, Priyanka Kasbekar, Murray F Brennan, Daniel G Coit, Vivian E Strong

Abstract readComparative Study
In one paragraph

Article in Journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  16. Article
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  18. Article
  19. miRNAs derived from plasma small extracellular vesicles predict organo-tropic metastasis of gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ping LiDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Chang-Ming HuangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Chao-Hui ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Ashley RussoDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Priyanka KasbekarDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Murray F BrennanDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Daniel G CoitDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Vivian E StrongDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID http://orcid.org/0000-0001-5044-1662

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
National Cancer Institute P30 CA008748National Key Clinical Specialty Discipline Construction Program of China [2012] 649NCI NIH HHS P30 CA008748Scientific and Technological Innovation Joint Capital Projects of Fujian Province 2016Y9031
6 · The paper itself

Abstract

BACKGROUND AND

objectivesGastric cancer (GC) outcomes differ between Asian and Western countries, even when controlling for contributing factors, but whether this difference holds true for China remains inadequately studied. We sought to compare the presentation, treatment, and outcomes of patients with GC undergoing curative intent (R0) resection between the US and China, and to ascertain whether geography/ institution is an independent predictor of disease-specific survival (DSS).

methodsData were analyzed from patients with GC undergoing R0 resection at high-volume cancer centers in the US (Memorial Sloan Kettering Cancer Center [MSKCC], n = 1378) and China (Fujian Medical University Union Hospital [FMUUH], n = 4262) between 2000 and 2014. Factors associated with DSS were examined by multivariate analysis.

resultsThe 5-year DSS ( P < 0.001) for all patients was better at MSKCC than at FMUUH, even among patients not receiving preoperative chemotherapy ( P < 0.001), but stratification by substage eliminated this difference ( P > 0.05). Factors independently associated with DSS included age, histology, tumor size, T category, N category, gastrectomy type, and preoperative chemotherapy, but not institution.

conclusionsAlthough the presentation of patients with GC between MSKCC and FMUUH differs, survival of patients with curatively resected GC, when matched for clinical stage, is comparable.

Indexed as

ChinaFemaleGastrectomyHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingStomach NeoplasmsSurvival RateTreatment OutcomeUnited StatesChinaEastern and Westernperioperative chemotherapyprognosisstomach cancerstomach neoplasmsUnited States

Identifiers

PMID30332517
PMCPMC6319936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.