Evidence map›Paper›PMID 30332474›Full record

ArticlePloS one2018

Chemical and molecular characterization of metabolites from Flavobacterium sp.

Vildan Enisoglu-Atalay, Belkis Atasever-Arslan, Bugra Yaman, Rumeysa Cebecioglu, Aykut Kul, Selma Ozilhan, Fatih Ozen, Tunc Catal

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 39 citations in OpenAlex.

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  7. Wild Mushrooms: A Hidden Treasure of Novel Bioactive Compounds.International journal of analytical chemistry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Vildan Enisoglu-AtalayIstanbul Research Application and Inovation Center (PROMER), Uskudar University, Uskudar, Istanbul, Turkey.
Belkis Atasever-ArslanDepartment of Molecular Biology and Genetics, Uskudar University, Uskudar, Istanbul, Turkey.
Bugra YamanIstanbul Research Application and Inovation Center (PROMER), Uskudar University, Uskudar, Istanbul, Turkey.
Rumeysa CebeciogluIstanbul Research Application and Inovation Center (PROMER), Uskudar University, Uskudar, Istanbul, Turkey.
Aykut KulPersonalized Medicine Application and Research Center (KIMER), Uskudar University, Uskudar, Istanbul, Turkey.
Selma OzilhanPersonalized Medicine Application and Research Center (KIMER), Uskudar University, Uskudar, Istanbul, Turkey.
Fatih OzenDepartment of Bioengineering, Uskudar University, Uskudar, Istanbul, Turkey.
Tunc CatalIstanbul Research Application and Inovation Center (PROMER), Uskudar University, Uskudar, Istanbul, Turkey.ORCID 0000-0003-2990-8680
Üsküdar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a Flavobacterium sp. is isolated from natural spring, and identified using molecular techniques. Extracellular and intracellular secondary metabolites are identified using solid phase microextraction gas chromatography-mass spectrometry and ultra performance liquid chromatography. Cytotoxic activity of the extracellular compounds produced by the Flavobacterium sp. and quercetin as the standard are measured using ECV304 human endothelial cells in vitro. Our results show that Flavobacterim sp. isolate has the highest percentage of similarity with Flavobacterium cheonhonense strain ARSA-15 (99%). Quercetin is detected as the major extracellular compound produced by the Flavobacterium sp. Methanol extract of Flavobacterium sp. resulted in a higher cell viability results when compared to DMSO extracts. Computational chemistry approach was used and it has been found that polar solvent (methanol) contributed to higher antioxidant activity. In conclusion, Flavobacterium sp. can be used to produce quercetin for industrial purposes.

Indexed as

DNA, BacterialBacterial Typing TechniquesBase CompositionChromatography, High Pressure LiquidComputer SimulationEndothelial CellsFatty AcidsFlavobacteriumFresh WaterGas Chromatography-Mass SpectrometryHumansPhylogenyRNA, Ribosomal, 16SSecondary MetabolismSequence Analysis, DNADNA, BacterialFatty AcidsRNA, Ribosomal, 16S

Identifiers

PMID30332474
PMCPMC6192653
OpenAlexW2897790618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.