ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Prevalence of and pathways to benzodiazepine use in Brazil: the role of depression, sleep, and sedentary lifestyle.
Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Pathways to chronic benzodiazepine use: a qualitative study of user and professional perspectives.BMC primary care · 2026Article
- Between prescription and deprescription: a qualitative study on the trajectory and challenges in the use of benzodiazepines among older adults.Frontiers in pharmacology · 2026Article
- Challenge of long-term benzodiazepine use in primary care: insights from a real-world cohort study in Catalonia.Family medicine and community health · 2025Article
- The effect of an intervention for organizing primary mental health care in Brazil: a study based on routine process indicators.BMC primary care · 2025Article
- Psychiatric drugs dispensing trends in the affected population following Brumadinho dam failure.Frontiers in public health · 2025Article
- Dispensing of zolpidem and benzodiazepines in Brazilian private pharmacies: a retrospective cohort study from 2014 to 2021.Frontiers in pharmacology · 2024Article
- [Factors associated with benzodiazepines dependence in insomnia patients].Revista medica del Instituto Mexicano del Seguro Social · 2023Observational
- 2023 Guidelines on the Diagnosis and Treatment of Insomnia in Adults - Brazilian Sleep Association.Sleep science (Sao Paulo, Brazil) · 2023Review
- Dispensing of psychotropic drugs in the Brazilian capital city before and during the COVID-19 pandemic (2018-2020).Frontiers in pharmacology · 2022Article
- Benzodiazepines utilization in Brazilian older adults: a population-based study.Revista de saude publica · 2022Article
- Epidemiologic assessment of benzodiazepine exposure among suicide deaths in Colorado, 2015-2017.BMC public health · 2020Article
- Benzodiazepine consumption in Brazil: considerations regarding a population-specific scenario.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
- Dependence on hypnotics: a comparative study between chronic users of benzodiazepines and Z-drugs.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
- Psychometric properties of the Benzodiazepine Dependence Self-Report Questionnaire - Portuguese Version (BENDEP-SRQ-PV).Trends in psychiatry and psychotherapyObservational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to determine the prevalence of benzodiazepine (BZD) use in Brazil and to investigate the direct and indirect effects of alcohol consumption, sedentary lifestyle (SL), depressive symptoms (DS), and sleep dissatisfaction (SD) on BZD use.
methodsThe Second Brazilian Alcohol and Drugs Survey (II BNADS) used stratified cluster probabilistic sampling to select 4,607 individuals aged 14 years and older from the Brazilian household population.
resultsThe lifetime and 12-month prevalence of BZD use was 9.8 and 6.1%, respectively. Older participants (age 40 and older) and women had higher rates. Alcohol use disorder, DS, and SD were significantly more prevalent in BZD users. The parallel multiple mediator model showed a positive direct effect of alcohol consumption on BZD use, with significant positive indirect effects of SL, SD, and DS as simultaneous mediators leading to higher BZD intake. Other statistically significant indirect pathways were DS alone, SD alone, and all of the above except SL.
conclusionThe prevalence of BZD use in Brazil is high compared to that of other countries. Knowledge of the main risk factors and pathways to consumption can guide prevention initiatives and underlie the development of better tailored and effective treatment strategies.
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