Evidence map›Paper›PMID 30328752›Full record

ArticleJournal of feline medicine and surgery2019

Relationship between total thyroxine, thyroid palpation and a clinical index in hyperthyroid and healthy cats and cats with other diseases.

Astrid Wehner, Ines Koehler, Sabine Ramspott, Katrin Hartmann

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Astrid WehnerCenter of Clinical Veterinary Medicine, Clinic of Small Animal Medicine, Ludwig Maximilian University, Munich, Germany.ORCID 0000-0002-2279-3609
Ines KoehlerCenter of Clinical Veterinary Medicine, Clinic of Small Animal Medicine, Ludwig Maximilian University, Munich, Germany.
Sabine RamspottCenter of Clinical Veterinary Medicine, Clinic of Small Animal Medicine, Ludwig Maximilian University, Munich, Germany.
Katrin HartmannCenter of Clinical Veterinary Medicine, Clinic of Small Animal Medicine, Ludwig Maximilian University, Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPresent-day diagnosis of hyperthyroidism is often established in the early stages where clinical signs and physical examination findings typically associated with the disease may not yet be present. The purpose of this study was to investigate thyroid palpation score (TPS), total thyroxine (T4), body weight, body condition score and a clinical scoring index, which assesses severity of illness and quality of life, in untreated hyperthyroid cats, healthy cats and cats with non-thyroidal illness.

methodsFifty-five cats with hyperthyroidism, 45 healthy cats and 327 euthyroid cats with non-thyroidal disease were prospectively enrolled. A Kruskal-Wallis test was used to determine any differences between metric data. A χ

resultsAlmost 80% of the hyperthyroid cats and up to 20% of the healthy cats and cats with non-thyroidal illness had a palpable thyroid gland. Median TPS in hyperthyroid cats was 2, which was significantly higher compared with the other groups. Although there was a significant correlation between TPS and T4 when evaluating all cats, this could not be demonstrated in the three subgroups. Hyperthyroid cats with larger thyroid glands (TPS >3) did not have higher T4 levels. Hyperthyroid cats with lower clinical scores had significantly higher T4 levels compared with hyperthyroid cats with higher scores. Hyperthyroid cats were older and had lower body weights and body condition scores than other cats. CONCLUSIONS AND RELEVANCE: Hyperthyroid cats were commonly found to have palpable thyroid glands, but they were smaller than previously reported.

Indexed as

Cat DiseasesHyperthyroidismAnimalsCatsPalpationProspective StudiesQuality of LifeSeverity of Illness IndexThyroid GlandThyroxineThyroxinebody condition scoreHyperthyroidismKarnofsky scorethyroid gland palpationthyroxine

Identifiers

PMID30328752
PMCPMC10814298
OpenAlexW2896754684

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.