Evidence map›Paper›PMID 30328104›Full record

ArticleThe Journal of comparative neurology2019

Whole mouse brain connectomics.

G Allan Johnson, Nian Wang, Robert J Anderson, Min Chen, Gary P Cofer, James C Gee, Forrest Pratson, Nicholas Tustison, Leonard E White

Open access · greenAbstract read
In one paragraph

Article in The Journal of comparative neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. From Circuits to Lifespan: Translating Mouse and Human Timelines with Neuroimaging-Based Tractography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Diffusion MRI Connections in the Octopus Brain.Experimental neurobiology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

G Allan JohnsonDepartment of Radiology, Duke Center for in vivo Microscopy, Duke Medical Center, Durham, North Carolina.ORCID 0000-0002-7606-5447
Nian WangDepartment of Radiology, Duke Center for in vivo Microscopy, Duke Medical Center, Durham, North Carolina.
Robert J AndersonDepartment of Radiology, Duke Center for in vivo Microscopy, Duke Medical Center, Durham, North Carolina.
Min ChenDepartments of Computer and Information Science, and Bioengineering, Penn Image Computing Lab, University of Pennsylvania, Philadelphia, Pennsylvania.
Gary P CoferDepartment of Radiology, Duke Center for in vivo Microscopy, Duke Medical Center, Durham, North Carolina.
James C GeeDepartments of Computer and Information Science, and Bioengineering, Penn Image Computing Lab, University of Pennsylvania, Philadelphia, Pennsylvania.
Forrest PratsonDepartment of Radiology, Duke Center for in vivo Microscopy, Duke Medical Center, Durham, North Carolina.
Nicholas TustisonDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia.
Leonard E WhiteDepartment of Neurology, Duke Medical Center, Durham, North Carolina.
Duke Medical Center · USUniversity of Pennsylvania · USDuke University · USUniversity of Virginia Medical Center · US

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
INTEGRATED CENTER FOR IN VIVO MICROSCOPYP41EB015897 · NIBIB · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2012 to 2017
$7.4M
Waxholm Space for Rodent NeuroinformaticsR01NS096720 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C · 2016 to 2019
$2.4M
Agilent Direct Drive 9.4T MRS/MRI ConsoleS10OD010683 · OD · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2012 to 2012
$597k
NEI NIH HHS P30 EY001583NIBIB NIH HHS P41 EB015897NIH HHS S10 OD010683NINDS NIH HHS R01 NS096720
6 · The paper itself

Abstract

Methods have been developed to allow quantitative connectivity of the whole fixed mouse brain by means of magnetic resonance imaging (MRI). We have translated what we have learned in clinical imaging to the very special domain of the mouse brain. Diffusion tensor imaging (DTI) of perfusion fixed specimens can now be performed with spatial resolution of 45 μm

Indexed as

AnimalsBrainConnectomeDiffusion Tensor ImagingImage Processing, Computer-AssistedMiceNeural PathwaysConnectomesmouse brainMR histologyMRI

Identifiers

PMID30328104
PMCPMC6467764
OpenAlexW2896054722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.