Evidence map›Paper›PMID 30328064›Full record

Trial reportEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2018

Clinical evaluation of a surface pre-reacted glass (S-PRG) filler-containing dental sealant placed with a self-etching primer/adhesive.

S Ntaoutidou, A Arhakis, K Tolidis, N Kotsanos

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04701294 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Evaluation of the Retention of a Sealant Based on Flowable Resin With Sprg and Another Based on Flowable Resin in First Permanent Molars:Randomized Controlled Clinical Trial in 12 Months

TypeinterventionalSponsorCatherine Christie Ruiz YasudaRan2021 to 2022Enrolled60ConditionsPit and Fissure SealantArmsGiomer Beautifil flow plusF03 Shofu-Japan, Tetric N flow ivoclar vivadent-Germany
NCT06922552 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Clinical Performance of Giomer Preceded by Etching Versus Resin-Based Sealants Applied on Permanent Molars Affected by Molar-Incisor Hypo-mineralization: A Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled56ConditionsMolar Incisor HypomineralizationArmsGiomer pit and fissure sealant with etching applied on Permanent Molars Affected by MIH, Resin based sealant applied on Permanent Molars Affected by MIH
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Restorative interventions and management of primary and permanent molars affected by molar incisor hypo-mineralization: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Bioactive materials with S-PRG filler in paediatric dentistry: a scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. The Current Strategies in Controlling Oral Diseases by Herbal and Chemical Materials.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

S NtaoutidouDepartment of Paediatric Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece. stefania.ntaoutidou@gmail.com.ORCID http://orcid.org/0000-0002-2819-0411
A ArhakisDepartment of Paediatric Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
K TolidisDepartment of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
N KotsanosDepartment of Paediatric Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo clinically evaluate the retention rates and caries-prevention effect of a resin-based, non-etch and rinse, self-etch primed pit and fissure sealant containing Sealant Pre-reacted Glass Ionomer Cement (S-PRG) fillers, in comparison to a conventional resin-based sealant over an 18-month period.

methodsThere were 81 children, aged 6-12 years old, who were randomly assigned to one of two sealant-groups, either the self-etch primed sealant (Beautisealant, Shofu) or the conventional etch and rinse sealant (Seal it, Spident). A total of 218 sealants of both groups were placed on first permanent molars with either sound surfaces (The International Caries Detection and Assessment System [ICDAS], code 0) or incipient enamel caries lesions (ICDAS code 1) according to the manufacturers' instructions. Each sealant restoration was independently evaluated in terms of retention and caries status at 6, 12 and 18 months. The data were statistically analysed with the Chi-squared test and z-test and the level of significance was preset at α = 0.05.

resultsThe differences between the complete retention rates of the two sealant groups were statistically significant in all periods of evaluation (p < 0.01). Survival rates of each sealant-group were comparable on sound (ICDAS 0) and enamel caries lesions (ICDAS1). Caries prevention effect of the two sealant groups was similar at the end of the evaluation period.

conclusionsThe clinical performance of the S-PRG filler-containing dental sealant placed with a self-etching primer was poor regarding its retention. Its significantly higher loss did not lead to more carious occlusal surfaces at the 18-month recall.

Indexed as

Dental CementsDental Restoration, PermanentChildDental CariesDental EtchingFemaleGlass Ionomer CementsHumansMaleMaterials TestingPit and Fissure SealantsDental CementsGlass Ionomer CementsPit and Fissure SealantsDental sealantsPre-reacted glass fillersResin-basedSelf-etch

Identifiers

PMID30328064
OpenAlexW2896531355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.