ArticleJournal of neurology2018
Perfusion-CT imaging in epileptic seizures.
Article in Journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 45 citations in OpenAlex.
- Review
- CT perfusion abnormalities in status epilepticus: associations with clinical characteristics, EEG, and outcome measures.Journal of neurology · 2026Article
- Functional Stroke Mimics: Patient Characteristics, CT-Based Multimodal Imaging and Long-Term Outcome in a Comparative Cohort Study.European journal of neurology · 2026Article
- Brain perfusion imaging in patients with status epilepticus, seizures, and IIC patterns.Clinical neurophysiology practice · 2026Review
- Editorial: Deep learning for high-dimensional sense, non-linear signal processing and intelligent diagnosis, vol II.Frontiers in psychiatry · 2026Article
- Cerebral computed tomography perfusion pattern in Todd's paralysis: A case series, unraveling diagnostic challenges and clinical implications.Radiology case reports · 2025Article
- Computed Tomography Perfusion Imaging: A Key Initial Test for Isolated Acute Aphasia in the Emergency Department.Revista de neurologia · 2025Article
- Attention-based multi-scale convolution and conformer for EEG-based depression detection.Frontiers in psychiatry · 2025Article
- Editorial: Deep learning for high-dimensional sense, non-linear signal processing and intelligent diagnosis.Frontiers in psychiatry · 2024Article
- Effectiveness of computed tomography perfusion imaging in stroke management.Frontiers in neurology · 2024Article
- Large-scale transient peri-ictal perfusion magnetic resonance imaging abnormalities detected by quantitative image analysis.Brain communications · 2023Article
- Prediction of cognitive impairment using higher order item response theory and machine learning models.Frontiers in psychiatry · 2023Article
- Electrographic Seizures in the Critically Ill.Neurologic clinics · 2022Review
- Diagnostic value of whole-brain computed tomographic perfusion imaging for suspected large artery occlusion stroke patients in emergency department.Acta neurologica Belgica · 2022Article
- Hyperperfusion Tmax mapping for nonconvulsive status epilepticus in the acute setting: A pilot case-control study.Epilepsia · 2022Article
- Epileptic seizures in the emergency room: clinical and electroencephalographic findings associated with brain perfusion patterns on computed tomography.Journal of neurology · 2022Article
- Recent developments in imaging of epilepsy.Current opinion in neurology · 2019Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPCT is used in the diagnosis of acute neurological syndromes, particularly stroke. We aimed to evaluate PCT abnormalities in patients with acute epileptic seizures or status epilepticus (SE).
methodsWe collected patients undergoing acute PCT for the suspicion of acute ischemic stroke (AIS), who received a final diagnosis of focal seizures or generalised seizures with a post-ictal deficit, with or without concomitant AIS. PCTs were retrospectively analysed for the presence of hyper- and hypoperfusion, and results correlated with delay from seizure onset, aetiology, type of seizures and the presence of electrical SE.
resultsHalf of the 43 consecutively identified patients had regional PCT abnormalities-hyperperfusion in 13 (30%) and hypoperfusion in 8 (19%)-and 4 (9%) had AIS. Among patients with hyperperfusion, six (46%) had a focal deficit during imaging acquisition (two a normal clinical status, one altered consciousness and four ongoing seizure); nine (69%) of these patients had a SE; none had a stroke. All patients with hypoperfusion had focal neurological deficit; three (37%) of them a simultaneous ischemic stroke (in the remaining five, hypoperfusion was considered to be related to the seizure post-ictal phase). In the 22 with normal perfusion, 9 had a focal deficit (10 a normal clinical status, 2 altered consciousness and 1 ongoing seizure); 3 had a SE, and 1 had a stroke. Patients with SE featured a higher prevalence of hyperperfusion (9/13 [69%] vs. 4/30 [13%] without SE, p = 0.00).
conclusionIn patients with acute epileptic seizures, regional hyperperfusion on PCT may suggest an ongoing or recently resolved SE, whereas hypoperfusion may be due to post-ictal state or simultaneous AIS. These observations might help attributing focal deficits to epileptic seizures rather than stroke, allowing for targeted therapy.
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