Evidence map›Paper›PMID 30327902›Full record

ArticleMedicine, health care, and philosophy2019

Research ethics aspects of experimentation with LSD on human subjects: a historical and ethical review.

Kristóf János Bodnár, Péter Kakuk

Abstract readHistorical Article
In one paragraph

Article in Medicine, health care, and philosophy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Key Characteristics and Development of Psychoceuticals: A Review.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kristóf János BodnárDepartment of Medical Humanities, School of Public Health, Institute of Behavioral Sciences, University of Debrecen, Debrecen, Hungary. bodnar.janos@sph.unideb.hu.
Péter KakukDepartment of Medical Humanities, School of Public Health, Institute of Behavioral Sciences, University of Debrecen, Debrecen, Hungary.

Funding

E-Education in Research Ethics: Central /Eastern EuropeR25TW007085 · FIC · UNION GRADUATE COLLEGE · PI GEFENAS, EUGENIJUS, PHILPOTT, SEAN M. · 2004 to 2017
$3.2M
FIC NIH HHS R25 TW007085Fogarty International Center R25TW007085
6 · The paper itself

Abstract

In this paper our aim is to examine whether research conducted on human participants with LSD-25 (lysergic acid diethylamide) raises unique research ethical questions or demands particular concerns with regard to the design, conduct and follow-up of these studies, and should this be the case, explore and describe those issues. Our analysis is based on reviewing publications up to date which examine the clinical, research and other uses of LSD and those addressing ethical and methodological concerns of these applications, just as some historical examinations of this subject. The first chapters of the paper give an overview regarding the history of LSD-research with human participants, healthy volunteers and patients alike. The remaining chapters have a focus on questions regarding the potential ethical issues of such human trials in the contemporary research ethics framework. We also consider briefly political and regulatory issues regarding this substance that possibly affect its clinical and research applications.

Indexed as

Ethics, ResearchHistory, 20th CenturyHistory, 21st CenturyHuman ExperimentationHumansLysergic Acid DiethylamidePhilosophy, MedicalLysergic Acid DiethylamideClinical trialLSD researchLysergic acid diethylamidePsychedelic researchResearch ethics

Identifiers

PMID30327902
PMCPMC6467737

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.