ReviewJournal of immunology research2018
Silicone-Induced Granuloma of Breast Implant Capsule (SIGBIC): Histopathology and Radiological Correlation.
Review in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 46 citations in OpenAlex.
- Research Progress in Biomedical Materials.Biomolecules · 2026Review
- Why Is the Baker Classification Inadequate for Classifying Silicone Implant Fibrous Capsules?Cureus · 2024Article
- Silicone Granuloma Mimicking a Lymphatic Metastasis in a Lung Cancer Patient: A Case Report.Journal of chest surgery · 2023Article
- Silicone-Induced Granulomas of Breast Implant Capsule (SIGBIC).Journal of the Belgian Society of Radiology · 2023Article
- Breast silicone implants' pericapsular impairment: current underdiagnosed status.Frontiers in surgery · 2023Review
- Progressive sensory ataxia and breast implant rupture, an uncommon presentation of a debated concept: a case report.BMC neurology · 2022Article
- Fundamentals of Breast Implant Illness and Device Imaging.International journal of inflammation · 2022Review
- Side effects in breast implants related to radiotherapy in breast cancer reconstructive surgery.Technical innovations & patient support in radiation oncology · 2021Article
- The contradiction of breast implant illness.Gland surgery · 2021Article
- Comparison of the Incidence of Capsular Formation in Two-Stage, Implant-Based Breast Reconstruction Using an Insertion Funnel and Sizer.BioMed research international · 2021Article
- The Breast Tumor Microenvironment: Could Silicone Breast Implant Elicit Breast Carcinoma?Breast cancer (Dove Medical Press) · 2021Article
- [Understanding Silicone Breast Implant-Associated Complications for Radiologists].Taehan Yongsang Uihakhoe chi · 2021Review
- Not All That Shines on a PET Scan Is Cancer: A Silicone-Induced Granuloma Masquerading as Malignancy.Clinics and practice · 2020Article
- Synchronous breast implant associated anaplastic large cell lymphoma (BIA-ALCL) and silicone induced granuloma of breast implant capsule (SIGBIC): What to learn.Radiology case reports · 2020Article
- Observational
- Palpable Lumps after Mastectomy: Radiologic-Pathologic Review of Benign and Malignant Masses.Radiographics : a review publication of the Radiological Society of North America, IncArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Currently, attention has been given to complications related to breast implants, especially due to the presence of anaplastic large cell lymphoma (ALCL) related to silicone implants. Many manuscripts attempt to associate silicone presence with clinical complaints reported by patients, while others try to demonstrate the mechanisms of silicone bleeding by permeability loss of breast implant surfaces. There also are reports of foreign body type reactions from implant fibrous capsule to silicone corpuscles. However, there seems to be no study that correlates the clinical, radiological, and histological correlations of these lesions. The objective of this review is to correlate radiological findings of silicone-induced granuloma of breast implant capsule (SIGBIC) from breast MRI (BMRI) scans and complementary findings of ultrasound (US) and positron emission tomography (PET) scan, and its histology originated from surgical breast implant capsulectomy. To make this correlation possible, we divided SIGBIC into three radiological findings: (1) intracapsular SIGBIC, (2) SIGBIC with extracapsular extension, and (3) mixed SIGBIC associated with seroma. Our experience demonstrates histological-radiological correlation in SIGBIC diagnosis. Knowledge of these findings may demonstrate its real importance in terms of public health and patient management. We believe that SIGBIC is currently underdiagnosed by lack of training, guidance, and management in our clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.