Evidence map›Paper›PMID 30327785›Full record

ArticleJournal of diabetes research2018

Five-Year Predictors of Insulin Initiation in People with Type 2 Diabetes under Real-Life Conditions.

Sandro Gentile, Felice Strollo, Francesca Viazzi, Giuseppina Russo, Pamela Piscitelli, Antonio Ceriello, Carlo Giorda, Piero Guida, Paola Fioretto, Roberto Pontremoli and 2 more

Abstract read
In one paragraph

Article in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Observational
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  7. Real-World Patterns of Basal Insulin Use with Other Diabetes Medications Among People with Type 2 Diabetes Between 2014 and 2020.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sandro GentileDepartment of Clinical and Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Felice StrolloDiabetes Center, San Raffaele Termini, Rome, Italy.ORCID 0000-0001-8917-5314
Francesca ViazziDepartment of Internal Medicine, University of Genoa and Policlinico San Martino, Genova, Italy.ORCID 0000-0003-4219-7043
Giuseppina RussoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0002-4565-3131
Pamela PiscitelliIRCSS Casa Sollievo della Sofferenza-Unit of Internal Medicine, Scientific Institute, San Giovanni Rotondo, Italy.
Antonio CerielloInstitut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomedica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.ORCID 0000-0002-7955-4684
Carlo GiordaDiabetes and Metabolism Unit ASL Turin 5, Chieri, Italy.
Piero GuidaStatistical Consultant, Associazione Medici Diabetologi (AMD), Rome, Italy.
Paola FiorettoDepartment of Medicine, University of Padua, Padua, Italy.
Roberto PontremoliDepartment of Internal Medicine, University of Genoa and Policlinico San Martino, Genova, Italy.ORCID 0000-0003-1238-872X
Salvatore De CosmoIRCSS Casa Sollievo della Sofferenza-Unit of Internal Medicine, Scientific Institute, San Giovanni Rotondo, Italy.ORCID 0000-0001-8787-8286
The Amd-Annals Study GroupAssociazione Medici Diabetologi (AMD), Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a real-life analysis of clinical and laboratory parameters, in orally treated T2DM patients aiming at identifying predictors of insulin treatment initiation. Overall, 366955 patients (55.8% males, age 65 ± 11 years, diabetes duration 7 ± 8 years) were followed up between 2004 and 2011. Each patient was analyzed step-by-step until either eventually starting insulin treatment or getting to the end of the follow-up period. Patients switching to insulin showed a worse global risk profile, longer disease duration (10 ± 9 years vs. 6 ± 7 years, respectively;

Indexed as

AgedBlood GlucoseDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinHumansHypoglycemic AgentsInsulinMaleMiddle AgedTriglyceridesBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinTriglycerides

Identifiers

PMID30327785
PMCPMC6169213

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.