Evidence map›Paper›PMID 30327725›Full record

ArticleJournal of ophthalmology2018

Anterior Chamber Flare as an Objective and Quantitative Noninvasive Method for Oculopathy in Transthyretin V30M Amyloidosis Patients.

João Beirão, Vasco Miranda, Beatriz Pinheiro-Torres, João Coelho, Maria-João Menéres, Pedro Menéres

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

João BeirãoInstituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.ORCID 0000-0001-8642-7010
Vasco MirandaCentro Hospitalar Porto, Porto, Portugal.
Beatriz Pinheiro-TorresAlimera Sciences, Alpharetta, USA.
João CoelhoCentro Hospitalar Porto, Porto, Portugal.ORCID 0000-0003-2261-5682
Maria-João MenéresCentro Hospitalar Porto, Porto, Portugal.
Pedro MenéresInstituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.
Centro Hospitalar do Porto · PTUniversidade do Porto · PTAlimera Sciences (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAssess the aqueous humor flare in transthyretin V30M amyloidosis patients (ATTRV30M). MATERIALS AND

methodsThis is a retrospective, cross-sectional, noninterventional comparative study including 28 ATTRV30M patients with a unilateral scalloped iris. For comparative analysis, the fellow eye, the nonscalloped iris eye, from each patient was used as control. All patients underwent aqueous humor flare meter and intraocular pressure (IOP) measurements.

resultsMean aqueous humor flare was significantly higher in the eyes with the scalloped iris than the control group with the nonscalloped iris (14.1 ± 2.2 versus 6.5 ± 0.9 pc/ms, respectively). No significant differences in IOP were found in the scalloped iris eyes than those in the nonscalloped iris control group (17.1 ± 0.8 versus 16.8 ± 0.7 mmHg, respectively). No significant correlation was not found between the flare and the IOP value within groups.

conclusionsIn this study, aqueous humor flare values in the scalloped iris eyes may be a valid marker for controlling the stage of the oculopathy in ATTRV30M patients.

Identifiers

PMID30327725
PMCPMC6171253
OpenAlexW2891212754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.