Evidence map›Paper›PMID 30327611›Full record

ArticleFrontiers in physiology2018

Acute NaCl Loading Reveals a Higher Blood Pressure for a Given Serum Sodium Level in African American Compared to Caucasian Adults.

Megan M Wenner, Erin P Paul, Austin T Robinson, William C Rose, William B Farquhar

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04244604 (The Effects of a High Salt Meal on Blood Flow Regulation), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04244604 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effects of a High Salt Meal on Blood Flow Regulation

TypeinterventionalSponsorIndiana UniversityRan2021 to 2025Enrolled71ConditionsSodium Excess, Racial Disparities, Blood Pressure, Cardiovascular Risk FactorArmsLow Sodium Meal (140 mg sodium chloride), High Sodium Meal (2500 mg sodium chloride)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Sex differences in central salt sensing in the human brain.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  6. Interplay of race and neighborhood deprivation on resting and ambulatory blood pressure in young adults.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Factors contributing to racial differences in neurogenic orthostatic hypotension.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Article
  13. Sodium restriction improves nocturia in patients at a cardiology clinic.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
  14. Neural control of cardiovascular function in black adults: implications for racial differences in autonomic regulation.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Review
  15. The Influence of Dietary Salt Beyond Blood Pressure.Current hypertension reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Megan M WennerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, United States.
Erin P PaulDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, United States.
Austin T RobinsonDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, United States.
William C RoseDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, United States.
William B FarquharDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, United States.
University of Delaware · US

Funding

VOLUMETRIC BREAST DENSITY ESTIMATION USING BREAST SURFACE RECONSTRUCTEDP20RR016472 · NCRR · UNIVERSITY OF DELAWARE · PI MENNELLA, PRINCY QUADROS · 2001 to 2011
$37.6M
Adverse Neurogenic Actions of Dietary SaltR01HL128388 · NHLBI · UNIVERSITY OF DELAWARE · PI FARQUHAR, WILLIAM B, STOCKER, SEAN D · 2016 to 2019
$2.6M
Sympathetic - Osmotic Interactions in HumansR15HL074851 · NHLBI · UNIVERSITY OF DELAWARE · PI FARQUHAR, WILLIAM B · 2004 to 2007
$460k
NCRR NIH HHS P20 RR016472NHLBI NIH HHS R01 HL128388NHLBI NIH HHS R15 HL074851
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blood pressurehypertonic salineosmolalityRAASrace

Identifiers

PMID30327611
PMCPMC6174209
OpenAlexW2895142487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.