Evidence map›Paper›PMID 30327495›Full record

Observational studySpinal cord2019

Analysis of risk factors for hyponatremia in patients with acute spinal cord injury: a retrospective single-institution study in Japan.

Hiroyuki Ohbe, Tomoaki Koakutsu, Shigeki Kushimoto

Open access · bronzeAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Spinal cord, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Construction and validation of a risk prediction model for hyponatremia caused by cervical spinal cord injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hiroyuki OhbeDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan. hohbey@gmail.com.
Tomoaki KoakutsuDepartment of Emergency and Critical Care Medicine/Emergency Center, Tohoku University Hospital, Sendai, Japan.
Shigeki KushimotoDepartment of Emergency and Critical Care Medicine/Emergency Center, Tohoku University Hospital, Sendai, Japan.
Tohoku University Hospital · JPUniversity of Tokyo Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective single-institution observational study.

objectiveSpinal cord injury (SCI) is associated with a high prevalence of hyponatremia, which can cause various clinical symptoms and increase mortality. We aimed to analyze the risk factors for hyponatremia in patients with acute SCI.

settingTrauma Center, Tohoku University Hospital, Japan

methodsWe reviewed the medical records of patients with SCI admitted between January 2008 and November 2016. Least angle regression analyses was performed to assess the association between hyponatremia and other parameters.

resultsOf the 213 enrolled patients, 85 (40%) had hyponatremia (serum Na < 135 mmol/L) whilst 19 (9%) had severe hyponatremia (serum Na < 130 mmol/L). Least angle regression analyses revealed that hyponatremia was significantly associated with higher American Spinal Injury Association impairment scale, nosocomial pneumonia, deep vein thrombosis, bradycardia, and surgery for SCI before developing hyponatremia. Severe hyponatremia was significantly associated with traumatic brain injury with an abbreviated injury scale score ≥3, higher American Spinal Injury Association impairment scale, bradycardia, vasopressors, and nosocomial pneumonia.

conclusionVarious factors including traumatic brain injury with an abbreviated injury scale score ≥3 and higher American Spinal Injury Association impairment scale may be associated with hyponatremia in patients with acute SCI. These factors can help clinicians identify and monitor SCI patients with a higher hyponatremia risk, and potentially help patients to avoid severe complications.

Indexed as

Acute DiseaseAdultAgedFemaleHumansHyponatremiaJapanMaleMiddle AgedRetrospective StudiesRisk FactorsSpinal Cord Injuries

Identifiers

PMID30327495
OpenAlexW2897609326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.