Evidence map›Paper›PMID 30327325›Full record

ArticleDevelopment (Cambridge, England)2018

The Hippo pathway effector Taz is required for cell morphogenesis and fertilization in zebrafish.

Chaitanya Dingare, Alina Niedzwetzki, Petra A Klemmt, Svenja Godbersen, Ricardo Fuentes, Mary C Mullins, Virginie Lecaudey

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. The essential role of TAZ in normal tissue homeostasis.Archives of pharmacal research · 2021
    Review
  12. Article
  13. Quantifying Tissue Tension in the Granulosa Layer After Laser Surgery.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. ThePhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  18. Article
  19. Workshop on Germ Cells.Frontiers in cell and developmental biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chaitanya DingareInstitute of Cell Biology and Neuroscience, Department of Developmental Biology of Vertebrates, Goethe Universität Frankfurt am Main, Max-von-Laue-Straße 13, 60438 Frankfurt am Main, Germany.ORCID 0000-0002-5116-4721
Alina NiedzwetzkiInstitute of Cell Biology and Neuroscience, Department of Developmental Biology of Vertebrates, Goethe Universität Frankfurt am Main, Max-von-Laue-Straße 13, 60438 Frankfurt am Main, Germany.
Petra A KlemmtInstitute of Cell Biology and Neuroscience, Department of Developmental Biology of Vertebrates, Goethe Universität Frankfurt am Main, Max-von-Laue-Straße 13, 60438 Frankfurt am Main, Germany.
Svenja GodbersenDevelopmental Biology, Institute for Biology I, Faculty of Biology, Albert-Ludwigs-Universität Freiburg, 79104 Freiburg, Germany.
Ricardo FuentesUniversity of Pennsylvania Perelman School of Medicine, Department of Cell and Developmental Biology, 421 Curie Blvd., Philadelphia, PA 19104, USA.
Mary C MullinsUniversity of Pennsylvania Perelman School of Medicine, Department of Cell and Developmental Biology, 421 Curie Blvd., Philadelphia, PA 19104, USA.ORCID 0000-0002-9979-1564
Virginie LecaudeyInstitute of Cell Biology and Neuroscience, Department of Developmental Biology of Vertebrates, Goethe Universität Frankfurt am Main, Max-von-Laue-Straße 13, 60438 Frankfurt am Main, Germany lecaudey@bio.uni-frankfurt.de.ORCID 0000-0002-8713-3425
Goethe University Frankfurt · DEUniversity of Pennsylvania · USUniversity of Freiburg · DE

Funding

Mechanisms Establishing Oocyte PolarityR01GM117981 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MULLINS, MARY C. · 2015 to 2018
$1.4M
NIGMS NIH HHS R01 GM117981
6 · The paper itself

Abstract

Hippo signaling is a critical pathway that integrates extrinsic and intrinsic mechanical cues to regulate organ size. Despite its essential role in organogenesis, little is known about its role in cell fate specification and differentiation. Here, we unravel a novel and unexpected role of the Hippo pathway effector Taz (

Indexed as

FertilizationMorphogenesisSignal TransductionAdherens JunctionsAnimalsBiomarkersCell PolarityCell ShapeCytochalasin DFemaleHippo KinasesInfertility, FemaleIntracellular Signaling Peptides and ProteinsMicrotubulesModels, BiologicalMutationBiomarkersCytochalasin DHippo KinasesIntracellular Signaling Peptides and ProteinsProtein Serine-Threonine KinasesSerine-Threonine Kinase 3stk3 protein, zebrafishTranscriptional Coactivator with PDZ-Binding Motif ProteinsWWTR1 protein, zebrafishZebrafish ProteinsFertilizationHippoMicropylar cellMicropyleTazZebrafish

Identifiers

PMID30327325
PMCPMC6262795
OpenAlexW2897692170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.