ArticlePediatric neurology2018
The Burden of Pediatric Neurocritical Care in the United States.
Article in Pediatric neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 48 citations in OpenAlex.
- The Effect of Foot Reflexology Massage on Delirium and Physiological Indicators in Children Admitted to Pediatric Intensive Care Unit: A Randomized Clinical Trial.TheScientificWorldJournal · 2026Trial
- Dynamic multimodal brain function monitoring enables quantitative severity grading and prognostic prediction in pediatric neurocritical care.Jornal de pediatria · 2026Article
- Sleep Management and Recovery After TBI in Kids (SMART-Kids): Pilot Trial Using Melatonin.Hospital pediatrics · 2026Article
- Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury.Neurocritical care · 2026Article
- Circadian rhythms in pediatric neurocritical care: interfaces and opportunities.Frontiers in neurology · 2026Review
- Time to treatment in pediatric patients with repeated episodes of status epilepticus.BMC neurology · 2025Observational
- Area-Level Socioeconomic Disadvantage and Post-PICU Outcomes in Children With an Acquired Brain Injury: Single-Center Retrospective Cohort, 2016-2023.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Extubation Failure and Timing to Tracheostomy in Children Surviving Acute Neurological Injury.Children (Basel, Switzerland) · 2025Article
- Multidisciplinary Consensus on Curricular Priorities for Pediatric Neurocritical Care Nursing Education: A Modified Delphi Study in the United States.Neurocritical care · 2024Article
- Exposure to Sedation and Analgesia Medications: Short-term Cognitive Outcomes in Pediatric Critical Care Survivors With Acquired Brain Injury.Journal of intensive care medicine · 2024Article
- Brain-Derived Neurotrophic Factor in Pediatric Acquired Brain Injury and Recovery.Biomolecules · 2024Review
- Post-PICU sleep efficiency and quality of life in infants and toddlers with acquired brain injury.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Characteristics and Outcomes of Children with Cerebral Sinus Venous Thrombosis.Neurocritical care · 2023Article
- Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children.Neurocritical care · 2023Review
- The Impact of Sleep Disturbances on Health-Related Quality of Life in Children With Acquired Brain Injury After Critical Care.Pediatric neurology · 2023Article
- Social Functioning and Autistic Behaviors in Youth Following Acquired Brain Injury.Children (Basel, Switzerland) · 2022Review
- Is Pediatric Intensive Care Trauma-Informed? A Review of Principles and Evidence.Children (Basel, Switzerland) · 2022Review
- Sleep disturbances in infants and young children following an acquired brain injury.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Exploring Trends in Neuromonitoring Use in a General Pediatric ICU: The Need for Standardized Guidance.Children (Basel, Switzerland) · 2022Article
- Sleep and Executive Functioning in Pediatric Traumatic Brain Injury Survivors after Critical Care.Children (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDisorders requiring pediatric neurocritical care (PNCC) affect thousands of children annually. We aimed to quantify the burden of PNCC through generation of national estimates of disease incidence, utilization of critical care interventions (CCI), and hospital outcomes.
methodsWe performed a retrospective cohort analysis of the Kids Inpatient Database over three years to evaluate pediatric traumatic brain injury, neuro-infection or inflammatory diseases, status epilepticus, stroke, hypoxic ischemic injury after cardiac arrest, and spinal cord injury. We evaluated use of CCI, death, length of stay, hospital charges, and poor functional outcome defined as receipt of tracheostomy or gastrostomy or discharge to a medical care facility.
resultsAt least one CCI was recorded in 67,058 (23%) children with a primary neurological diagnosis, and considered a PNCC admission. Over half of PNCC admissions had at least one chronic condition, and 23% were treated in children's hospitals. Mechanical ventilation was the most common CCI, but utilization of CCIs varied significantly by diagnosis. Among PNCC admissions, 8110 (12%) children died during hospitalization and 14,067 (21%) children had poor functional outcomes. PNCC admissions cumulatively accounted for over 1.5 million hospital days and over $4 billion in hospital costs in the study years. Most PNCC admissions, across all diagnoses, had prolonged hospitalizations (more than one week) with an average cost of $39.9 thousand per admission.
conclusionsThis large, nationally representative study shows PNCC diseases are a significant public health burden with substantial risk to children's health. More research is needed to improve outcomes in these vulnerable children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.