ArticleBurns : journal of the International Society for Burn Injuries2019
Evaluating clinical observation versus Spatial Frequency Domain Imaging (SFDI), Laser Speckle Imaging (LSI) and thermal imaging for the assessment of burn depth.
Article in Burns : journal of the International Society for Burn Injuries, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Experimental Burn Induction in Laboratory Animals: A Scoping Review of Methods, Reproducibility, Operator-Dependent Variability, and Relevance to Soft Tissue Reconstruction and Repair.Bioengineering (Basel, Switzerland) · 2026Review
- Impact of the β correction factor on the accuracy of speckle contrast imaging measurements.Biomedical optics express · 2026Article
- Article
- Thermal imaging in biomedical research: a non-invasive technology for animal models.Frontiers in veterinary science · 2025Review
- Multi-frequency spatial frequency domain imaging: a depth-resolved optical scattering model to isolate scattering contrast in thin layers of skin.Journal of biomedical optics · 2024Article
- Review of machine learning for optical imaging of burn wound severity assessment.Journal of biomedical optics · 2024Review
- Non-invasive medical imaging technology for the diagnosis of burn depth.International wound journal · 2024Review
- Progress in the application of artificial intelligence in skin wound assessment and prediction of healing time.American journal of translational research · 2024Review
- MicroRNA-155 mediates multiple gene regulations pertinent to the role of human adipose-derived mesenchymal stem cells in skin regeneration.Frontiers in bioengineering and biotechnology · 2024Article
- Triage ofBiomedical optics express · 2023Article
- Training generative adversarial networks for optical property mapping using synthetic image data.Biomedical optics express · 2022Article
- Bioreactor design and validation for manufacturing strategies in tissue engineering.Bio-design and manufacturing · 2022Article
- Spatial frequency domain imager based on a compact multiaperture camera: testing and feasibility for noninvasive burn severity assessment.Journal of biomedical optics · 2021Article
- Application of contrast-enhanced ultrasound in the diagnosis of burn depth.Annals of translational medicine · 2021Article
- Evaluation of Hemodynamics in a Murine Hindlimb Ischemia Model Using Spatial Frequency Domain Imaging.Lasers in surgery and medicine · 2021Article
- Characterizing reduced scattering coefficient of normal human skin across different anatomic locations and Fitzpatrick skin types using spatial frequency domain imaging.Journal of biomedical optics · 2021Article
- Quantifying dermal microcirculatory changes of neuropathic and neuroischemic diabetic foot ulcers using spatial frequency domain imaging: a shade of things to come?BMJ open diabetes research & care · 2020Article
- Real-time video-rate perfusion imaging using multi-exposure laser speckle contrast imaging and machine learning.Journal of biomedical optics · 2020Article
- Handheld multispectral imager for quantitative skin assessment in low-resource settings.Journal of biomedical optics · 2020Article
- Spatial Frequency Domain Imaging (SFDI) of clinical burns: A case report.Burns open : an international open access journal for burn injuries · 2020Article
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7 authors.
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Abstract
While clinical examination is needed for burn severity diagnosis, several emerging technologies aim to quantify this process for added objectivity. Accurate assessments become easier after burn progression, but earlier assessments of partial thickness burn depth could lead to earlier excision and grafting and subsequent improved healing times, reduced rates of scarring/infection, and shorter hospital stays. Spatial Frequency Domain Imaging (SFDI), Laser Speckle Imaging (LSI) and thermal imaging are three non-invasive imaging modalities that have some diagnostic ability for noninvasive assessment of burn severity, but have not been compared in a controlled experiment. Here we tested the ability of these imaging techniques to assess the severity of histologically confirmed graded burns in a swine model. Controlled, graded burn wounds, 3cm in diameter were created on the dorsum of Yorkshire pigs (n=3, 45-55kg) using a custom-made burn tool that ensures consistent pressure has been employed by various burn research groups. For each pig, a total of 16 burn wounds were created on the dorsal side. Biopsies were taken for histological analysis to verify the severity of the burn. Clinical analysis, SFDI, LSI and thermal imaging were performed at 24 and 72h after burn to assess the accuracy of each imaging technique. In terms of diagnostic accuracy, using histology as a reference, SFDI (85%) and clinical analysis (83%) performed significantly better that LSI (75%) and thermography (73%) 24h after the burn. There was no statistically significant improvement from 24 to 72h across the different imaging modalities. These data indicate that these imaging modalities, and specifically SFDI, can be added to the burn clinicians' toolbox to aid in early assessment of burn severity.
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