Evidence map›Paper›PMID 30326899›Full record

ReviewJournal of nanobiotechnology2018

Recent advancements in the use of exosomes as drug delivery systems.

Edwin J Bunggulawa, Wei Wang, Tieying Yin, Nan Wang, Colm Durkan, Yazhou Wang, Guixue Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of nanobiotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 282 papers.

0numbers the graph read from it
0cells of the map it votes in
282citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

282 citing papers in PubMed.

  1. Article
  2. Article
  3. Biology and Therapeutic Potential of Exosomes, Targeted Drug Delivery.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
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  11. Article
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  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review

222 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edwin J BunggulawaKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing University, No 174 Shazheng Street, Shapingba District, Chongqing, 400044, People's Republic of China.
Wei WangKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing University, No 174 Shazheng Street, Shapingba District, Chongqing, 400044, People's Republic of China.
Tieying YinKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing University, No 174 Shazheng Street, Shapingba District, Chongqing, 400044, People's Republic of China. tieying_yin@cqu.edu.cn.
Nan WangNanoscience Centre, Department of Engineering, University of Cambridge, JJ Thomson Avenue, Cambridge, CB3 0FF, UK.
Colm DurkanNanoscience Centre, Department of Engineering, University of Cambridge, JJ Thomson Avenue, Cambridge, CB3 0FF, UK.
Yazhou WangKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing University, No 174 Shazheng Street, Shapingba District, Chongqing, 400044, People's Republic of China. yazhou_wang@cqu.edu.cn.
Guixue WangKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing University, No 174 Shazheng Street, Shapingba District, Chongqing, 400044, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell.

Indexed as

Drug Delivery SystemsAnimalsExosomesHumansHydrogen-Ion ConcentrationNanoparticlesNeoplasmsDelivery propertiesExosomeExtracellular vesicles

Identifiers

PMID30326899
PMCPMC6190562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.