ArticleBMC psychiatry2018
The burden of depressive disorders in South Asia, 1990-2016: findings from the global burden of disease study.
Article in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- The ASHA (Hope) Project: Testing an Integrated Depression Treatment and Economic Strengthening Intervention in Rural Bangladesh: A Pilot Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Trial
- The Multifaceted Pathophysiology of Major Depressive Disorder: Integrating Neurobiology, Genetics, and Systems-level Perspectives.Current neurovascular research · 2026Review
- Factors associated with common mental disorder symptoms and lived experiences among adults with hypertension in Nepal: a mixed-methods study.Frontiers in epidemiology · 2026Article
- Article
- Relationship Between the Socio-Demographic Index and the Burden of Depressive Disorders in Asia (2010-2021): A Population Based Study.Health science reports · 2025Article
- Socio-demographic factors associated with mental health disorders among rural women in Mymensingh, Bangladesh.Frontiers in psychiatry · 2025Article
- Article
- Trends in Prevalent Cases and Disability-Adjusted Life-Years of Depressive Disorders Worldwide: Findings From the Global Burden of Disease Study From 1990 to 2021.Depression and anxiety · 2025Article
- Recent advances in the synthesis of antidepressant derivatives: pharmacologic insights for mood disorders.3 Biotech · 2024Review
- Clinical effect of acupuncture at ghost points combined with fluoxetine hydrochloride on mild-to-moderate depression.World journal of psychiatry · 2024Article
- Temporal and spatial trend analysis of all-cause depression burden based on Global Burden of Disease (GBD) 2019 study.Scientific reports · 2024Article
- Projecting the 10-year costs of care and mortality burden of depression until 2032: a Markov modelling study developed from real-world data.The Lancet regional health. Western Pacific · 2024Article
- Living with depression and diabetes: A qualitative study in Bangladesh and Pakistan.PLOS global public health · 2024Article
- The association between living alone and depressive symptoms in older adults population: evidence from the China Health and Retirement Longitudinal Study.Frontiers in public health · 2024Article
- Pregnancy, spousal connectedness, and young married women's mental health: an analysis of the Bangladesh adolescent health and wellbeing survey.Archives of women's mental health · 2023Article
- Depression and Its Phytopharmacotherapy-A Narrative Review.International journal of molecular sciences · 2023Review
- Exploring the Lived Experience on Recovery from Major Depressive Disorder (MDD) among Women Survivors and Five CHIME Concepts: A Qualitative Study.Behavioral sciences (Basel, Switzerland) · 2023Article
- Validating the Children's Depression Inventory-2: Results from the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study.PloS one · 2023Article
- A scoping review of community-based mental health intervention for children and adolescents in South Asia.Global mental health (Cambridge, England) · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlobally, depressive disorders are one of the most common forms of mental illness. Using data from the most recent Global Burden of Disease, Injury, and Risk Factor Study 2016 (GBD 2016), we aimed to describe the burden of disease attributable to depressive disorders in terms of prevalence and disability-adjusted life years (DALYs) in South Asia countries (namely India, Pakistan, Bangladesh, Nepal and Bhutan).
methodsGBD 2016 used epidemiological data on depressive disorders (major depression and dysthymia) from South Asia and a Bayesian meta-regression tool (DisMod-MR 2.1) to model prevalence and DALYs of depressive disorders by age, sex, country and year. DALYs were calculated from the years lived with disability (YLDs), derived from the prevalence of depressive disorders and disability weights, obtained from a community and internet-based surveys. The analyses adjusted for comorbidity, data sources and multiple modelling, and estimates were presented with 95% uncertainty intervals (UI).
resultsIn 2016, the age-standardised prevalence of depressive disorders in South Asia was 3.9% (95% UI: 3.6-4.2%), 4.4% (95% UI: 4.4-4.8%) in Bangladesh, 3.9% (95% UI: 3.6-4.2%) in India, 3.0% (95% UI: 2.8-3.3%) in Pakistan, 4.0% (95% UI: 3.7-4.3%) in Nepal and 3.7% (95% UI: 3.4-4.1%) in Bhutan. In South Asia, depressive disorders accounted for 9.8 million DALYs (95% UI: 6.8-13.2 million) or 577.8 (95% UI: 399.9-778.9) per 100,000 population in 2016. Of these, major depressive disorders (MDD) accounted for 7.8 million DALYs (95% UI: 5.3-10.5 million). India generated the largest numbers of DALYs due to depressive disorders and MDD, followed by Bangladesh and Pakistan. DALYs due to depressive disorders were highest in females and older adults (75-79 years) across all countries.
conclusionOur findings show the substantial public health burden of depressive disorders in South Asian populations and healthcare systems. Given the scale of depressive disorders, improvement in overall population health is possible if South Asian countries prioritise the prevention and treatment of depressive disorders.
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