Evidence map›Paper›PMID 30326847›Full record

ArticleBMC medical imaging2018

Dual-phase whole-heart imaging using image navigation in congenital heart disease.

Danielle M Moyé, Tarique Hussain, Rene M Botnar, Animesh Tandon, Gerald F Greil, Adrian K Dyer, Markus Henningsson

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Lymphatic pathway evaluation in congenital heart disease using 3D whole-heart balanced steady state free precession and T2-weighted cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Danielle M MoyéDepartment of Pediatrics, Division of Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, USA. dmoye@stanfordalumni.org.ORCID 0000-0002-3870-8982
Tarique HussainDepartment of Pediatrics, Division of Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, USA.
Rene M BotnarDivision of Imaging Sciences, King's College London, London, UK.
Animesh TandonDepartment of Pediatrics, Division of Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, USA.
Gerald F GreilDepartment of Pediatrics, Division of Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, USA.
Adrian K DyerDepartment of Pediatrics, Division of Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, USA.
Markus HenningssonDivision of Imaging Sciences, King's College London, London, UK.
Children's Medical Center · USKing's College London · GBPontificia Universidad Católica de Chile · CLSouthwestern Medical Center · US

Funding

MAPS ARRAY DIAGNOSTIC DETECTION OF EXFOLIATED CELLSR43CA088641 · NCI · DISCOVERY PARTNERS INTERNATIONAL, INC. · PI SELIGMANN, BRUCE E. · 2000 to 2000
$100k
REDOX CHEMISTRY &BIOCHEMISTRY OF ORGANOSULFUR COMPOUNDSR01HL015104 · NHLBI · UNIVERSITY OF ARIZONA · PI GLASS, RICHARD S · 1985 to 1992
–
British Heart Foundation PG/15/104/31913British Heart Foundation RG/12/1/29262Department of HealthEngineering and Physical Sciences Research Council WT 088641/Z/09/Z
6 · The paper itself

Abstract

backgroundDual-phase 3-dimensional whole-heart acquisition allows simultaneous imaging during systole and diastole. Respiratory navigator gating and tracking of the diaphragm is used with limited accuracy. Prolonged scan time is common, and navigation often fails in patients with erratic breathing. Image-navigation (iNAV) tracks movement of the heart itself and is feasible in single phase whole heart imaging. To evaluate its diagnostic ability in congenital heart disease, we sought to apply iNAV to dual-phase sequencing.

methodsHealthy volunteers and patients with congenital heart disease underwent dual-phase imaging using the conventional diaphragmatic-navigation (dNAV) and iNAV. Acquisition time was recorded and image quality assessed. Sharpness and length of the right coronary (RCA), left anterior descending (LAD), and circumflex (LCx) arteries were measured in both cardiac phases for both approaches. Qualitative and quantitative analyses were performed in a blinded and randomized fashion.

resultsIn volunteers, there was no significant difference in vessel sharpness between approaches (p > 0.05). In patients, analysis showed equal vessel sharpness for LAD and RCA (p > 0.05). LCx sharpness was greater with dNAV (p < 0.05). Visualized length with iNAV was 0.5 ± 0.4 cm greater than that with dNAV for LCx in diastole (p < 0.05), 1.0 ± 0.3 cm greater than dNAV for LAD in diastole (p < 0.05), and 0.8 ± 0.7 cm greater than dNAV for RCA in systole (p < 0.05). Qualitative scores were similar between modalities (p = 0.71). Mean iNAV scan time was 5:18 ± 2:12 min shorter than mean dNAV scan time in volunteers (p = 0.0001) and 3:16 ± 1:12 min shorter in patients (p = 0.0001).

conclusionsImage quality of iNAV and dNAV was similar with better distal vessel visualization with iNAV. iNAV acquisition time was significantly shorter. Complete cardiac diagnosis was achieved. Shortened acquisition time will improve clinical applicability and patient comfort.

Indexed as

AdolescentAdultCase-Control StudiesChildFemaleHeart Defects, CongenitalHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance Imaging, CineMaleRandom AllocationCongenital heart diseaseDual phase imagingRespiratory motion correctionSteady-state free precession MRI

Identifiers

PMID30326847
PMCPMC6192322
OpenAlexW2897762647

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.