Evidence map›Paper›PMID 30326692›Full record

ArticleAsian spine journal2019

Anterior Bone Loss in Cervical Disc Arthroplasty.

David Christopher Kieser, Derek Thomas Cawley, Takashi Fujishiro, Celeste Tavolaro, Simon Mazas, Louis Boissiere, Ibrahim Obeid, Vincent Pointillart, Jean Marc Vital, Olivier Gille

Open access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. The lexicon for periprosthetic bone loss versus osteolysis after cervical disc arthroplasty: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  2. Osteolysis after cervical disc arthroplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020
    Pooled it
  3. Article
  4. Article
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  7. Clinical and biomechanical effects of bone-implant interface gap after cervical disc replacement.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  8. Article
  9. Risk factors of bone loss after Prestige-LP cervical disc arthroplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  10. Clinical management of bone loss in cervical total disc arthroplasty: literature review and treatment recommendations.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Review
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  14. Changes in the centre of rotation and the anterior bone loss of the vertebral body in Mobi-C artificial disc replacement segments after cervical hybrid surgery: a retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
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  19. Observational
  20. [Analysis of infuence factors of anterior bone loss after cervical disc arthroplasty and its effect on effectiveness].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

David Christopher KieserL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Derek Thomas CawleyL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Takashi FujishiroL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Celeste TavolaroL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Simon MazasL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Louis BoissiereL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Ibrahim ObeidL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Vincent PointillartL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Jean Marc VitalL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Olivier GilleL'Institut de la Colonne Vertébrale, CHU Pellegrin, Bordeaux, France.
Hôpital Pellegrin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective, longitudinal observational study. PURPOSE: To describe the natural history of anterior bone loss (ABL) in cervical disc arthroplasty (CDA) and introduce a classification system for its assessment. OVERVIEW OF LITERATURE: ABL has recently been recognized as a complication of CDA, but its cause and clinical effects remain unknown.

methodsPatients with non-keeled CDA (146) were retrospectively reviewed. X-rays were examined at 6 weeks, 3, 6, 9, 12, 18, and 24 months, and annually thereafter for a minimum of 5 years. These were compared with the initial postoperative X-rays to determine the ABL. Visual Analog Scale pain scores were recorded at 3 months and 5 years. Neck Disability Index was recorded at postoperative 5 years. The natural history was determined and a classification system was introduced.

resultsComplete radiological assessment was available for 114 patients with 156 cervical disc replacements (CDRs) and 309 endplates (average age, 45.3 years; minimum, 28 years; maximum, 65 years; 57% females). ABL occurred in 57.1% of CDRs (45.5% mild, 8.3% moderate, and 3.2% severe) and commenced within 3 months of the operation and followed a benign course, with improvement in the bone stock after initial bone resorption. There was no relationship between ABL degree and pain or functional outcome, and no implants were revised.

conclusionsABL is common (57.1%). It occurs at an early stage (within 3 months) and typically follows a non-progressive natural history with stable radiographic features after the first year. Most ABL cases are mild, but severe ABL occurs in approximately 3% of CDAs. ABL does not affect the patients' clinical outcome or the requirement for revision surgery. Surgeons should thus treat patients undergoing CDA considering ABL.

Indexed as

Avascular necrosisBone lossCervical disc replacementDisc arthroplastyOsteolysis

Identifiers

PMID30326692
PMCPMC6365779
OpenAlexW2896250657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.