ArticleStereotactic and functional neurosurgery2018
Safety and Utility of Hybrid Depth Electrodes for Seizure Localization and Single-Unit Neuronal Recording.
Article in Stereotactic and functional neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seizure outcomes and complications associated with stereoelectroencephalography versus subdural electrodes for invasive monitoring in epilepsy surgery: a meta-analysis.Frontiers in neurology · 2025Pooled it
- Hitting the Sulcus With a More Tangential Angle May Result in Resistance Felt During Implantation of Stereotactic Electroencephalography Electrodes.Neurosurgery practice · 2026Article
- Single-Neuron Recordings Research in Children: Ethical Considerations, Feasibility, Technical Aspects, and Scientific Opportunities.Pediatric neurosurgery · 2026Review
- Microelectrode Implantation in Human Insula: Technical Challenges and Recording Insights.Brain sciences · 2025Article
- Advancements in Surgical Therapies for Drug-Resistant Epilepsy: A Paradigm Shift towards Precision Care.Neurology and therapy · 2025Review
- Using noise to distinguish between system and observer effects in multimodal neuroimaging.Frontiers in computational neuroscience · 2025Article
- Simultaneous invasive and non-invasive recordings in humans: A novel Rosetta stone for deciphering brain activity.Journal of neuroscience methods · 2024Review
- Scalable, flexible carbon fiber electrode thread arrays for three-dimensional probing of neurochemical activity in deep brain structures of rodents.Biosensors & bioelectronics · 2023Article
- The human brain: The final frontier and the wild west.The Journal of clinical investigation · 2023Article
- Article
- Placement of Stereotactic Electroencephalography Depth Electrodes Using the Stealth Autoguide Robotic System: Technical Methods and Initial Results.Operative neurosurgery (Hagerstown, Md.) · 2022Article
- Article
- How Human Single-Neuron Recordings Can Help Us Understand Cognition: Insights from Memory Studies.Brain sciences · 2021Review
- Insights into human cognition from intracranial EEG: A review of audition, memory, internal cognition, and causality.Journal of neural engineering · 2020Review
- Cellular Classes in the Human Brain Revealed In Vivo by Heartbeat-Related Modulation of the Extracellular Action Potential Waveform.Cell reports · 2020Article
- Microelectrode recordings in human epilepsy: a case for clinical translation.Brain communications · 2020Review
- Stimulation Mapping Using Stereoelectroencephalography: Current and Future Directions.Frontiers in neurology · 2020Review
- Epilepsy Benchmarks Area III: Improved Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects.Epilepsy currentsArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundInvasive electrode monitoring provides more precise localization of epileptogenic foci in patients with medically refractory epilepsy. The use of hybrid depth electrodes that include microwires for simultaneous single-neuron monitoring is becoming more widespread.
objectiveTo determine the safety and utility of hybrid depth electrodes for intracranial monitoring of medically refractory epilepsy.
methodsWe reviewed the medical charts of 53 cases of medically refractory epilepsy operated on from 2006 to 2017, where both non-hybrid and hybrid microwire depth electrodes were used for intracranial monitoring. We assessed the localization accuracy and complications that arose to assess the relative safety and utility of hybrid depth electrodes compared with standard electrodes.
resultsA total of 555 electrodes were implanted in 52 patients. The overall per-electrode complication rate was 2.3%, with a per-case complication rate of 20.8%. There were no infections or deaths. Serious or hemorrhagic complications occurred in 2 patients (0.4% per-electrode risk). Complications did not correlate with the use of any particular electrode type, and hybrids were equally as reliable as standard electrodes in localizing seizure onset zones.
conclusionsHybrid depth electrodes appear to be as safe and effective as standard depth electrodes for intracranial monitoring and provide unique opportunities to study the human brain at single-neuron resolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.