ArticlePancreas
Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer.
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Article in Pancreas. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Pancreatic cancer-related diabetes and type 2 diabetes differ in multiple aspects of glucose homeostasis.Diabetologia · 2025Article
- Pancreatogenic diabetes: Pathophysiology, diagnosis, and management challenges.World journal of gastrointestinal surgery · 2025Review
- Cost-Effectiveness of Biomarker-Associated Early Pancreatic Cancer Detection in New-Onset Diabetes.JAMA network open · 2025Article
- Effect of Sodium-Glucose Co-Transporter 2 Inhibitors Combined with Metformin on Pancreatic Cancer Cell Lines.International journal of molecular sciences · 2024Article
- Challenges of Managing Type 3c Diabetes in the Context of Pancreatic Resection, Cancer and Trauma.Journal of clinical medicine · 2024Review
- A Reduced Pancreatic Polypeptide Response is Associated With New-onset Pancreatogenic Diabetes Versus Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2023Article
- Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.Diabetes · 2023Review
- Development of a Clinical Prediction Model for Diabetes in Chronic Pancreatitis: The PREDICT3c Study.Diabetes care · 2023Article
- Predictors of Glycemic Outcomes at 1 Year Following Pediatric Total Pancreatectomy With Islet Autotransplantation.Diabetes care · 2022Article
- Pancreatogenic Diabetes in Children With Recurrent Acute and Chronic Pancreatitis: Risks, Screening, and Treatment (Mini-Review).Frontiers in pediatrics · 2022Review
- Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review.Pancreas · 2021Review
- Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee.Journal of pediatric gastroenterology and nutrition · 2021Article
- Early detection of pancreatic cancer.The lancet. Gastroenterology & hepatology · 2020Review
- Pancreatogenic diabetes, acute pancreatitis management, and pancreatic tuberculosis: Appraising the present and setting goals for the future.United European gastroenterology journal · 2020Article
- Pathological Mechanisms in Diabetes of the Exocrine Pancreas: What's Known and What's to Know.Frontiers in physiology · 2020Review
- Chronic Pancreatitis: Managing a Difficult Disease.The American journal of gastroenterology · 2020Review
- Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus.Clinical and translational gastroenterology · 2019Article
- Is Screening for Pancreatic Cancer in High-Risk Individuals One Step Closer or a Fool's Errand?Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Article
- Article
- Screening for pancreatic cancer has the potential to save lives, but is it practical?Expert review of gastroenterology & hepatologyReview
Corrections and comments
- Erratum issued
Authors and funding
20 authors at 15 institutions in 2 countries.
Phil A Hart
Dana K AndersenDivision of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Kieren J MatherDivision of Endocrinology and Metabolism, Indiana University School of Medicine, Indianapolis, IN.
Alicia C Castonguay
Mandeep BajajSection of Endocrinology, Diabetes and Metabolism, Baylor College of Medicine, Houston, TX.
Melena D BellinDepartments of Pediatrics and Surgery, University of Minnesota Medical School, Minneapolis, MN.
David BradleyDiabetes and Metabolism Research Center, Division of Endocrinology, Diabetes and Metabolism, The Ohio State University Wexner Medical Center, Columbus, OH.
Noemy ContrerasDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX.
Aida HabtezionDivision of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA.
Murray KorcDepartments of Medicine, and Biochemistry and Molecular Biology, Indiana University School of Medicine, the Melvin and Bren Simon Cancer Center, and the Pancreatic Cancer Signature Center, Indianapolis, IN.
Yogish KudvaDivision of Endocrinology, Mayo Clinic College of Medicine, Rochester, MN.
Maxim S PetrovDepartment of Surgery, University of Auckland, Auckland, New Zealand.
David C WhitcombDepartments of Medicine, Cell Biology and Molecular Physiology, and Human Genetics, University of Pittsburgh, and UPMC.
Dhiraj YadavDivision of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Ying YuanDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX.
Jo Ann S RinaudoCancer Biomarker Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD.
Sudhir SrivastavaCancer Biomarker Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD.
Jose SerranoDivision of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Mark O GoodarziDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC)
National Institutes of Health · USThe Ohio State University Wexner Medical Center · USThe University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USCedars-Sinai Medical Center · USCommunity Cancer Center · USIndiana University – Purdue University Indianapolis · USMayo Clinic · USMayo Clinic in Arizona · USNational Institute of Diabetes and Digestive and Kidney Diseases · USStanford University · USUniversity of Auckland · NZUniversity of Minnesota Medical Center · USUniversity of Pittsburgh · USUniversity of Pittsburgh Medical Center · US
Funding
Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer: Coordinating and Data Management Center (CSCPDPC-CDMC)U01DK108328 · NIDDK · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Liang Li, Suyu Liu · 2015 to 2026
$32.8MTranslation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4MIndiana University (IU) Clinical Center for Chronic Pancreatitis Clinical Research NetworkU01DK108323 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Jeffrey James Easler, Evan L Fogel · 2015 to 2026
$6.5MUPMC Clinical Center for the Study of Chronic Pancreatitis and DiabetesU01DK108306 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Frederico G. S. Toledo, Dhiraj Yadav · 2015 to 2026
$6.4MThe Stanford Clinical Center for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic CancerU01DK108300 · NIDDK · STANFORD UNIVERSITY · PI Sohail Z Husain, Walter Gwang-Up Park · 2015 to 2026
$6.3MPathophysiology, Epidemiology, and Prevention of Pancreatogenic Diabetes - Administrative SupplementU01DK108314 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI Mark Goodarzi, Stephen J. Pandol · 2015 to 2026
$6.1MThe Exocrine and Endocrine Pancreas in Type 2 Diabetes, Pancreatitis and Cancer (Admin Supplement)U01DK108288 · NIDDK · MAYO CLINIC ROCHESTER · PI Santhi Swaroop Vege · 2015 to 2026
$5.9MThe Ohio State University Pancreatic Disorders Network (OSU-PDN)U01DK108327 · NIDDK · OHIO STATE UNIVERSITY · PI CONWELL, DARWIN LEWIS, HART, PHILIP A. · 2015 to 2024
$5.5MDYSBIOTIC MICROBIOME IN PANCREATITIS, DIABETES, AND PANCREATIC CANCERU01DK108326 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI FISHER, WILLIAM E · 2015 to 2024
$5.2MNIDDK NIH HHS L30 DK118657NIDDK NIH HHS P30 DK097512NIDDK NIH HHS U01 DK108288NIDDK NIH HHS U01 DK108300NIDDK NIH HHS U01 DK108306NIDDK NIH HHS U01 DK108314NIDDK NIH HHS U01 DK108323NIDDK NIH HHS U01 DK108326NIDDK NIH HHS U01 DK108327NIDDK NIH HHS U01 DK108328
Abstract
Pancreatogenic diabetes mellitus is most commonly the result of chronic pancreatitis but can also occur secondary to pancreatic cancer. The early identification of pancreatogenic diabetes and distinction from the more prevalent type 2 diabetes are clinically significant; however, currently, there is no validated method to differentiate these diabetes subtypes. We describe a study, "Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: the DETECT study," that seeks to address this knowledge gap. The DETECT study is a multicenter study that will examine differences in hormone and glucose excursions after a mixed meal test. The study will also create a biorepository that will be used to evaluate novel diagnostic biomarkers for differentiating these diabetes subtypes.
Indexed as
Research DesignAdultAgedBiomedical ResearchClinical Studies as TopicDiabetes MellitusDiagnostic Tests, RoutineHumansMiddle AgedMulticenter Studies as TopicPancreatic NeoplasmsPancreatitisPancreatitis, ChronicReproducibility of ResultsSensitivity and Specificity
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.