ArticlePancreas
INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort Study: Design and Rationale for INSPPIRE 2 From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer.
Article in Pancreas. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Trial
- Acute and Recurrent Pancreatitis in Children: Insights into Etiology and Clinical Course from a Retrospective Single-Center Study.Children (Basel, Switzerland) · 2026Article
- Age-associated outcomes of ERCP in pediatric chronic pancreatitis.Pediatric research · 2026Article
- Pain characteristics and multimodal analgesia in children hospitalised with pancreatitis: A retrospective study from a tertiary paediatric centre in India.Indian journal of anaesthesia · 2026Article
- Utility and utilization of transabdominal ultrasound in pediatric patients with acute recurrent or chronic pancreatitis.Journal of pediatric gastroenterology and nutrition · 2026Article
- A recurrence prediction model based on serological indicators in children with acute pancreatitis without pancreaticobiliary anatomical abnormalities.Frontiers in pediatrics · 2026Article
- Advancing the Diagnosis and Treatment of Early Chronic Pancreatitis Through Innovation in Imaging and Biomarker Profiling-A Narrative Review.Life (Basel, Switzerland) · 2025Review
- Patient and Family Input to Determine Experiences and Research Interests in Pediatric Pancreatitis: An INSPPIRE-2 Study.Pancreas · 2025Article
- Impact of Elevated Serum Triglycerides on Children with Acute Recurrent or Chronic Pancreatitis from INSPPIRE-2.The Journal of pediatrics · 2025Article
- Bone health in children with recurrent and chronic pancreatitis: A multi-center cross sectional analysis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2023Article
- An assessment of pancreatology education in North American pediatric gastroenterology fellowship programs.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022Article
- Consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer: achievements and future directions.Current opinion in gastroenterology · 2021Review
- Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee.Journal of pediatric gastroenterology and nutrition · 2021Article
- Fat-soluble Vitamin Deficiency is Common in Children With Chronic Pancreatitis Undergoing Total Pancreatectomy With Islet Autotransplantation.Journal of pediatric gastroenterology and nutrition · 2021Article
- Clinical and Practice Variations in Pediatric Acute Recurrent or Chronic Pancreatitis: Report From the INSPPIRE Study.Journal of pediatric gastroenterology and nutrition · 2020Article
- Advanced imaging techniques for chronic pancreatitis.Abdominal radiology (New York) · 2020Review
- Childhood Pancreatitis and Risk for Incident Diabetes in Adulthood.Diabetes care · 2020Article
- Chronic Pancreatitis: Managing a Difficult Disease.The American journal of gastroenterology · 2020Review
- Web-based cognitive-behavioral intervention for pain in pediatric acute recurrent and chronic pancreatitis: Protocol of a multicenter randomized controlled trial from the study of chronic pancreatitis, diabetes and pancreatic cancer (CPDPC).Contemporary clinical trials · 2020Article
- Risk Factors for Rapid Progression From Acute Recurrent to Chronic Pancreatitis in Children: Report From INSPPIRE.Journal of pediatric gastroenterology and nutrition · 2019Article
Corrections and comments
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Authors and funding
34 authors at 20 institutions in 4 countries.
Funding
Abstract
We created the INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE (INSPPIRE 2) cohort to study the risk factors, natural history, and outcomes of pediatric acute recurrent pancreatitis and chronic pancreatitis (CP). Patient and physician questionnaires collect information on demographics, clinical history, family and social history, and disease outcomes. Health-related quality of life, depression, and anxiety are measured using validated questionnaires. Information entered on paper questionnaires is transferred into a database managed by Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer's Coordinating and Data Management Center. Biosamples are collected for DNA isolation and analysis of most common pancreatitis-associated genes.Twenty-two sites (18 in the United States, 2 in Canada, and 1 each in Israel and Australia) are participating in the INSPPIRE 2 study. These sites have enrolled 211 subjects into the INSPPIRE 2 database toward our goal to recruit more than 800 patients in 2 years. The INSPPIRE 2 cohort study is an extension of the INSPPIRE cohort study with a larger and more diverse patient population. Our goals have expanded to include evaluating risk factors for CP, its sequelae, and psychosocial factors associated with pediatric acute recurrent pancreatitis and CP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.