ArticleJournal of veterinary internal medicine2018
Comparison of electroencephalographic findings with hippocampal magnetic resonance imaging volumetry in dogs with idiopathic epilepsy.
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Assessment of Oxidative Stress-Related Markers and Inflammatory Proteins in Serum and CSF Samples of Dogs with Different Types of Epilepsy.Antioxidants (Basel, Switzerland) · 2026Article
- Comparative subcutaneous and submuscular implantation of an electroencephalography device for long term electroencephalographic monitoring in dogs.Frontiers in veterinary science · 2024Article
- Hippocampal expression of the cannabinoid receptor type 1 in canine epilepsy.Scientific reports · 2023Article
- Clinical and Magnetic Resonance Imaging (MRI) Features, Tumour Localisation, and Survival of Dogs with Presumptive Brain Gliomas.Veterinary sciences · 2022Article
- Dogs as a Natural Animal Model of Epilepsy.Frontiers in veterinary science · 2022Review
- Peri-ictal magnetic resonance imaging characteristics in dogs with suspected idiopathic epilepsy.Journal of veterinary internal medicine · 2021Article
- Companion animal models of neurological disease.Journal of neuroscience methods · 2020Review
- Interictal Single-Voxel Proton Magnetic Resonance Spectroscopy of the Temporal Lobe in Dogs With Idiopathic Epilepsy.Frontiers in veterinary science · 2020Article
- Comparison of electroencephalographic findings with hippocampal magnetic resonance imaging volumetry in dogs with idiopathic epilepsy.Journal of veterinary internal medicine · 2018Article
- Correlation between semiautomated magnetic resonance imaging volumetry of the cingulate gyrus and interictal epileptiform discharge lateralization in dogs with idiopathic epilepsy.Journal of veterinary internal medicineArticle
- Semiautomatic volumetry of the temporal lobes of the brain and correlation with electroencephalography results in dogs with assumed idiopathic epilepsy.Journal of veterinary internal medicineArticle
- Status Epilepticus After Electrocution Injury in a Dog.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn humans, temporal lobe epilepsy (TLE), is a type of focal epilepsy occurring mainly in the mesial TLE (mTLE), commonly associated with hippocampal sclerosis (HS).
objectivesAccording to recent studies, TLE might also occur in dogs and could be associated with hippocampal atrophy (HA)/HS. To date, hippocampal lesions have not been correlated with electroencephalographic (EEG) findings in epileptic dogs. ANIMALS: An EEG examination, brain magnetic resonance imaging, and volumetric assessment of the hippocampus were performed in 16 nonepileptic and 41 epileptic dogs.
methodsIn this retrospective study, the presence and localization of EEG-defined epileptiform discharges (EDs) was blindly evaluated. The hippocampus was measured and assessed for unilateral atrophy. The results of EEG and volumetric findings were correlated to determine whether the functional epileptic focus is equivalent to structural changes.
resultsThe median hippocampal asymmetric ratio (AR) in epileptic dogs was significantly greater than in the control group (P < .001). Using a cut-off threshold AR of >6%, 56% (23/41) of the dogs were characterized with unilateral HA. Of those animals, 35% (8/23) had EDs in the temporal leads and 26% (6/23) had no EDs. In 88% (7/8) of dogs with EDs in the temporal leads that had unilateral HA, the EDs correlated with the side of the decreased hippocampal volume. CONCLUSIONS AND CLINICAL IMPORTANCE: The results indicate an association between the presence of EDs detectable on EEG and a decrease in the unilateral hippocampal volume in some cases of canine idiopathic epilepsy that might reflect features of human mTLE.
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