Evidence map›Paper›PMID 30325010›Full record

ArticleClinical and experimental immunology2019

Th17 responses to pneumococcus in blood and adenoidal cells in children.

E Oliver, C Pope, E Clarke, C Langton Hewer, A D Ogunniyi, J C Paton, T Mitchell, R Malley, A Finn

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

E OliverSchool of Cellular and Molecular Medicine, Biomedical Sciences Building, University of Bristol, Bristol, UK.ORCID 0000-0002-1211-1942
C PopeSchool of Cellular and Molecular Medicine, Biomedical Sciences Building, University of Bristol, Bristol, UK.
E ClarkeVaccines and Immunity Theme, MRC Unit The Gambia, Fajara, The Gambia.
C Langton HewerBristol Royal Hospital for Children, Bristol, UK.
A D OgunniyiAustralian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Adelaide, Australia.
J C PatonResearch Centre for Infectious Diseases, Department of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia.
T MitchellInstitute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
R MalleyDivision of Infectious Diseases, Department of Medicine, Children's Hospital and Harvard Medical School, Boston, MA, USA.
A FinnSchool of Cellular and Molecular Medicine, Biomedical Sciences Building, University of Bristol, Bristol, UK.
University of Bristol · GBUniversity of Adelaide · AUBoston Children's Hospital · USBristol Royal Hospital for Children · GBMRC Unit the Gambia · GMUniversity of Birmingham · GB

Funding

Medical Research Council MC_EX_MR/M007529/1Medical Research Council MC_EX_MR/R006148/1Medical Research Council MC_UP_A900_1115
6 · The paper itself

Abstract

Pneumococcal infections cause a large global health burden, and the search for serotype-independent vaccines continues. Existing conjugate vaccines reduce nasopharyngeal colonization by target serotypes. Such mucosal effects of novel antigens may similarly be important. CD4

Indexed as

AdenoidsAdolescentCells, CulturedChildChild, PreschoolHumansImmunologic MemoryInfantInterleukin-17Interleukin-22InterleukinsPneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeTh17 CellsVaccines, ConjugateIL17A protein, humanInterleukin-17Interleukin-22InterleukinsPneumococcal VaccinesVaccines, ConjugatecytokineshumanT cellsvaccination

Identifiers

PMID30325010
PMCPMC6330644
OpenAlexW2897580385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.