Evidence map›Paper›PMID 30324905›Full record

ArticleeLife2018

Firefly genomes illuminate parallel origins of bioluminescence in beetles.

Timothy R Fallon, Sarah E Lower, Ching-Ho Chang, Manabu Bessho-Uehara, Gavin J Martin, Adam J Bewick, Megan Behringer, Humberto J Debat, Isaac Wong, John C Day and 12 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 162 citations in OpenAlex.

  1. Article
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  4. Glow in the D-ARK: a new bioluminescent species ofRoyal Society open science · 2025
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  13. The complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2025
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  15. Novel viruses in the familiesmicroPublication biology · 2025
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  16. Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 14 institutions in 4 countries.

Timothy R Fallon *Whitehead Institute for Biomedical Research, Cambridge, United States.ORCID 0000-0002-3048-7679
Sarah E Lower *Department of Molecular Biology and Genetics, Cornell University, Ithaca, United States.ORCID 0000-0003-0889-3344
Ching-Ho ChangDepartment of Biology, University of Rochester, Rochester, United States.ORCID 0000-0001-9361-1190
Manabu Bessho-UeharaDepartment of Environmental Biology, Chubu University, Kasugai, Japan.ORCID 0000-0002-7388-464X
Gavin J MartinDepartment of Biology, Brigham Young University, Provo, United States.ORCID 0000-0002-8989-2601
Adam J BewickDepartment of Genetics, University of Georgia, Athens, United States.
Megan BehringerBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, United States.
Humberto J DebatCenter of Agronomic Research, National Institute of Agricultural Technology, Córdoba, Argentina.ORCID 0000-0003-3056-3739
Isaac WongDepartment of Biology, University of Rochester, Rochester, United States.ORCID 0000-0003-4877-5748
John C DayCentre for Ecology and Hydrology (CEH), Wallingford, United Kingdom.ORCID 0000-0002-5483-4487
Anton SuvorovDepartment of Biology, Brigham Young University, Provo, United States.ORCID 0000-0003-3898-9195
Christian J SilvaDepartment of Biology, University of Rochester, Rochester, United States.ORCID 0000-0002-9803-5249
Kathrin F Stanger-HallDepartment of Plant Biology, University of Georgia, Athens, United States.
David W HallDepartment of Genetics, University of Georgia, Athens, United States.ORCID 0000-0001-7708-6656
Robert J SchmitzDepartment of Genetics, University of Georgia, Athens, United States.ORCID 0000-0001-7538-6663
David R NelsonDepartment of Microbiology Immunology and Biochemistry, University of Tennessee HSC, Memphis, United States.ORCID 0000-0003-0583-5421
Sara M LewisDepartment of Biology, Tufts University, Medford, United States.
Shuji ShigenobuNIBB Core Research Facilities, National Institute for Basic Biology, Okazaki, Japan.ORCID 0000-0003-4640-2323
Seth M BybeeDepartment of Biology, Brigham Young University, Provo, United States.
Amanda M LarracuenteDepartment of Biology, University of Rochester, Rochester, United States.ORCID 0000-0001-5944-5686
Yuichi ObaDepartment of Environmental Biology, Chubu University, Kasugai, Japan.ORCID 0000-0003-2108-4947
Jing-Ke WengWhitehead Institute for Biomedical Research, Cambridge, United States.ORCID 0000-0003-3059-0075
University of Georgia · USBrigham Young University · USUniversity of Rochester · USWhitehead Institute for Biomedical Research · USArizona State University · USBucknell University · USChubu University · JPMonterey Bay Aquarium Research Institute · USNational Agricultural Technology Institute · ARNational Institute for Basic Biology · JPPlant (United States) · USTufts University · USUK Centre for Ecology & Hydrology · GBUniversity of Tennessee Health Science Center · US

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
The evolutionary and functional genomics of satellite DNAR35GM119515 · NIGMS · UNIVERSITY OF ROCHESTER · PI Amanda Marie Larracuente · 2016 to 2026
$4.0M
Experiment.com https://experiment.com/projects/illuminating-the-firefly-genomeGeorgia Research Alliance Lars G. Ljungdahl Distinguished InvestigatorNational Institute for Basic Biology Cooperative Research Program, 12-202National Science Foundation Graduate Student FellowshipNational Science Foundation MCB-1818132NIGMS NIH HHS 5R35-GM119515-03NIGMS NIH HHS R35 GM119515NIGMS NIH HHS T32 GM007287Pew Charitable Trusts Pew Scholar Program in the Biomedical Sciences
6 · The paper itself

Abstract

Fireflies and their luminous courtships have inspired centuries of scientific study. Today firefly luciferase is widely used in biotechnology, but the evolutionary origin of bioluminescence within beetles remains unclear. To shed light on this long-standing question, we sequenced the genomes of two firefly species that diverged over 100 million-years-ago: the North American

Indexed as

Evolution, MolecularAnimalsColeopteraFirefliesGenome, InsectLuciferases, FireflyLuminescent ProteinsMolecular Sequence AnnotationLuciferases, FireflyLuminescent ProteinsAquatica lateralisbioluminescencefireflygeneticsgenomicsIgnelater luminosusluciferasePhotinus pyralis

Identifiers

PMID30324905
PMCPMC6191289
OpenAlexW2784711332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.