Observational studyPediatric surgery international2018
Epidemiology of Hirschsprung disease in California from 1995 to 2013.
Observational study in Pediatric surgery international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation of Trans-Anal Endorectal Pull-Through Outcomes in Hirschsprung's Disease in Different Age Groups: A Comprehensive Systematic Review.Archives of Iranian medicine · 2024Pooled it
- Review
- Epidemiology and Surgical Management of Hirschsprung's Disease in France: A 12-Year Retrospective Analysis (2012-2023).Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- EMB is essential for enteric nervous system development mediated by PI3K signaling.Genome medicine · 2025Article
- The burden of delayed diagnosis in Hirschsprung disease: insights from a Paediatric Colorectal Centre in South Africa.BMC pediatrics · 2025Article
- Histopathologic Concerns and Diagnostic Challenges in Hirschsprung's Disease: An Eastern European Single-Center Observational Study.Life (Basel, Switzerland) · 2025Article
- Meconium-Related Obstruction and Clinical Outcomes in Term and Preterm Infants.JAMA network open · 2025Article
- Hirschsprung disease.Nature reviews. Disease primers · 2023Review
- Diagnosis of Hirschsprung disease by hydrocolonic sonography in children.European radiology · 2022Article
- Clinical outcomes and risk factors for postoperative complications in children with Hirschsprung's disease.American journal of translational research · 2022Article
- Emergency Department Pediatric Readiness and Potentially Avoidable Transfers.The Journal of pediatrics · 2021Observational
- Development of Clinical Referral Score Model for Early Diagnosis of Hirschsprung's Disease in Suspected Pediatric Patients.Healthcare (Basel, Switzerland) · 2021Article
- Pan-enteric neuropathy and dysmotility are present in a mouse model of short-segment Hirschsprung disease and may contribute to post-pullthrough morbidity.Journal of pediatric surgery · 2021Article
- The Prevalence and Clinical Profile of Hirschsprung's Disease at a Tertiary Hospital in Bahrain.Cureus · 2021Article
- Early and long-term complications following transanal pull through Soave technique in infants with Hirschsprung's disease.Medicine and pharmacy reports · 2019Article
- Ultrasound Evaluation of Perianal Diseases in Infants.Journal of medical ultrasoundReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study seeks to update current epidemiology of Hirschsprung disease (HD) in California.
methodsUsing data from the California Office of Statewide Health Planning and Development Linked Birth (1995-2012) and Patient Discharge Databases (1995-2013), patients from either dataset with an ICD-9 diagnosis code of HD (751.3) or procedure code of Soave (48.41), Duhamel (48.65), or Swenson/other pull-through (48.49) were included. Patients > age 18 during their first admission were excluded.
resultsOf 9.3 million births, 2,464 patients were identified. Incidence was 2.2 cases/10,000 live births, with rates peaking at 2.9/10,000 births in 2002. Incidence was highest among African American (4.1/10,000) and Asian/Pacific Islander (2.5/10,000) births. Most were male (n = 1652, 67.1%). Sixty patients (2.4%) had Down syndrome. The median gestational age at birth was 38 weeks 6 days (interquartile range [IQR] 37 weeks 1 day-40 weeks 1 day). Mortality during the first year of life was 1.7%. Median age at death was 14.5 days (IQR 0-113 days).
conclusionThis is one of the largest population-based studies of HD. In California, the incidence of HD is stable, risk is highest among African American children, and the mortality rate is < 2%.
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