Evidence map›Paper›PMID 30324464›Full record

ArticleMedical & biological engineering & computing2019

Imaging study of pseudo-CT images of superposed ultrasound deformation fields acquired in radiotherapy based on step-by-step local registration.

Hongfei Sun, Tao Lin, Kai Xie, Liugang Gao, Jianfeng Sui, Xinye Ni

Abstract read
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In one paragraph

Article in Medical & biological engineering & computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hongfei SunThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Xinglong Street 29#, Changzhou, 213003, China.
Tao LinThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Xinglong Street 29#, Changzhou, 213003, China.
Kai XieThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Xinglong Street 29#, Changzhou, 213003, China.
Liugang GaoThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Xinglong Street 29#, Changzhou, 213003, China.
Jianfeng SuiThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Xinglong Street 29#, Changzhou, 213003, China.
Xinye NiThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Xinglong Street 29#, Changzhou, 213003, China. nxy2000@aliyun.com.
Changzhou No.2 People's Hospital · CNNanjing Medical University · CN

Funding

Natural Science Foundation of Jiangsu Province BK20151181
6 · The paper itself

Abstract

The purpose of this study is to create a new pseudo-computed tomography (CT) imaging approach under superposed ultrasound (US) deformation fields based on step-by-step local registration. Scanned CT and US 3D image datasets of three patients with postoperative cervical carcinoma were selected, including CT (CTsim) and US images (USsim) acquired during simulated positioning process and cone beam CT (CBCT) and US images for positioning verification (USpv) acquired after treatment for 10 times. Regions of interest such as urinary bladders were segmented out and accepted local registration to obtain different deformation fields. These deformation fields were successively performed according to their order and then applied to localized CT images to obtain pseudo-CT (CTps). After filtering, we obtained the final correct pseudo-CT (CTpsf). The pseudo-CT based on the mask of the whole imaging region of US images (WCTps) were acquired as control. Then, we compared CTpsf, CTps, WCTps, and CBCT in terms of their similarity in anatomical structure and differences in pseudo-CT and CTsim in terms of dosimetry. Structural similarity degree between CTpsf and CBCT was larger compared with that between CTps and WCTps. Target regions and dosages of endangered organs between CTpsf and CTsim were different under the same calculation conditions based on the Monte Carlo algorithm. Compared with the VMAT plan of CTsim, the pass rate of CTpsf in γ analysis under the standards of 2% dosage difference and 2-mm distance difference was 91.8%. The imaging quality of CTpsf was better compared with WCTps and CTps. It exhibited high similarity with CBCT in anatomical structure and had favorable application prospect in adaptive radiotherapy. Graphical abstract The local deformation registration is performed between the ultrasound images based on different regions of interest, and then stepwise applied to localized CT images to obtain pseudo-CT. After filtering, the corrected pseudo CT image is obtained.

Indexed as

Cone-Beam Computed TomographyFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalRadiotherapy, Computer-AssistedRadiotherapy DosageTomography, X-Ray ComputedUltrasonographyUterine Cervical NeoplasmsImage-guided radiotherapyPseudo-CTUltrasound

Identifiers

PMID30324464
OpenAlexW2897696571

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.