ArticleEuropean radiology2019
Added value of diffusion-weighted imaging to conventional MRI for predicting fascial involvement of soft tissue sarcomas.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Evaluation of magnetic resonance imaging parameters and compliance with guidelines in soft tissue sarcomas.BMC cancer · 2026Article
- Soft-tissue sarcoma: modified grading method improves the accuracy of preoperative MRI in predicting patient outcomes.European radiology · 2025Article
- Synovial Sarcoma in the Extremity: Diversity of Imaging Features for Diagnosis and Prognosis.Cancers · 2023Review
- [Tumor Margin Infiltration in Soft Tissue Sarcomas: Prediction Using 3T MRI Texture Analysis].Taehan Yongsang Uihakhoe chi · 2022Article
- MRI after Whoops procedure: diagnostic value for residual sarcoma and predictive value for an incomplete second resection.Skeletal radiology · 2021Article
- Added-value of advanced magnetic resonance imaging to conventional morphologic analysis for the differentiation between benign and malignant non-fatty soft-tissue tumors.European radiology · 2021Article
- The accuracy of a novel sonographic scanning and reporting protocol to survey for soft tissue sarcoma local recurrence.Skeletal radiology · 2020Article
- Can we use MRI to detect clinically silent recurrent soft-tissue sarcoma?European radiology · 2020Article
- Can radiomics improve the prediction of metastatic relapse of myxoid/round cell liposarcomas?European radiology · 2020Article
- Multidisciplinary treatment of soft tissue sarcomas: An update.World journal of clinical oncology · 2020Review
- Soft tissue sarcoma: DWI and DCE-MRI parameters correlate with Ki-67 labeling index.European radiology · 2020Observational
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study was conducted to evaluate the added value of diffusion-weighted imaging (DWI) to conventional magnetic resonance imaging (MRI) for predicting fascial involvement of soft tissue sarcomas located in close proximity to fascial boundaries.
methodsThis retrospective study included 29 patients with surgically resected soft tissue sarcomas located in proximity to deep fascia and with a curvilinear tail-like hyperintensity in the adjacent fascia on T2-weighted images. All patients underwent conventional MRI and DWI at 3.0 T and had detailed histologic reports on involvement of fascia. Two musculoskeletal radiologists with 21 and 1 year of experience independently reviewed conventional MRI and conventional imaging with added DWI. Readers scored their confidence for tumor involvement of fascia using a three-point scale. Diagnostic performance (area under the curve [Az]) of the two MRI sets was assessed with receiver-operating characteristic curve analysis.
resultFascial involvement was present in 22/29 patients (75.9%). Both readers showed improvement in diagnostic performance with the addition of DWI (Az, from 0.545 to 0.792 and from 0.646 to 0.792 for reader 1 and reader 2, respectively). Adding DWI did not improve sensitivity or specificity for either reader (p > 0.05). Interobserver agreement for the confidence scores improved from fair to moderate with the addition of DWI (κ, from 0.390 to 0.560).
conclusionsAdding DWI to conventional MRI improved diagnostic performance on prediction of fascial involvement of soft tissue sarcomas located in proximity to fascia, without significant improvement in sensitivity or specificity. KEY POINTS: • Adding DWI to conventional MRI improved readers' confidence level for the prediction of fascial involvement of soft tissue sarcomas that are close to the deep fascia. • Addition of DWI also improved interobserver agreement. • Conversely, compared with conventional MRI, adding DWI did not significantly improve the sensitivity or specificity for the detection of fascial involvement.
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