ArticleEuropean radiology2019
Six-year prospective evaluation of second-look US with volume navigation for MRI-detected additional breast lesions.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 26 citations in OpenAlex.
- Real-time virtual sonography for prone-position breast MRI: technical feasibility and accuracy in locating 125 breast lesions.European radiology experimental · 2026Article
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- Clinical application of vein visualization apparatus AccuVeinJournal of medical case reports · 2025Article
- Evaluation of the intramammary distribution of breast lesions detected by MRI but not conventional second-look B-mode ultrasound using an MRI/ultrasound fusion technique.BMC medical imaging · 2024Article
- A review of MRI (CT)/US fusion imaging in treatment of breast cancer.Journal of medical ultrasonics (2001) · 2023Review
- Impact of the systematic introduction of tomosynthesis on breast biopsies: 10 years of results.La Radiologia medica · 2023Article
- Lean Perspectives in an Organizational Change in a Scientific Direction of an Italian Research Institute: Experience of the Cancer Institute of Bari.International journal of environmental research and public health · 2022Article
- Prospective Evaluation of Ultrasound in a Novel Position with MRI Virtual Navigation for MRI-Detected Only Breast Lesions: A Pilot Study of a More Efficient and Economical Method.Diagnostics (Basel, Switzerland) · 2022Article
- Prevalence of Patients Affected by Fibromyalgia in a Cohort of Women Underwent Mammography Screening.Healthcare (Basel, Switzerland) · 2021Article
- MRI versus Mammography plus Ultrasound in Women at Intermediate Breast Cancer Risk: Study Design and Protocol of the MRIB Multicenter, Randomized, Controlled Trial.Diagnostics (Basel, Switzerland) · 2021Article
- Second-Generation 3D Automated Breast Ultrasonography (Prone ABUS) for Dense Breast Cancer Screening Integrated to Mammography: Effectiveness, Performance and Detection Rates.Journal of personalized medicine · 2021Article
- Radiomic Feature Reduction Approach to Predict Breast Cancer by Contrast-Enhanced Spectral Mammography Images.Diagnostics (Basel, Switzerland) · 2021Article
- Extended Latissimus Dorsi Kite Flap (ELD-K Flap): Revisiting an Old Place for a Total Autologous Breast Reconstruction in Patients with Medium to Large Breasts.Aesthetic plastic surgery · 2021Article
- Predicting Molecular Subtypes of Breast Cancer with Mammography and Ultrasound Findings: Introduction of Sono-Mammometry Score.Radiology research and practice · 2021Article
- Radiomic Analysis in Contrast-Enhanced Spectral Mammography for Predicting Breast Cancer Histological Outcome.Diagnostics (Basel, Switzerland) · 2020Article
- Article
- Diagnostic challenges and potential early indicators of breast periprosthetic anaplastic large cell lymphoma: A case report.Medicine · 2020Article
- Efficient Anomaly Detection with Generative Adversarial Network for Breast Ultrasound Imaging.Diagnostics (Basel, Switzerland) · 2020Article
- Elite VABB 13G: A New Ultrasound-Guided Wireless Biopsy System for Breast Lesions. Technical Characteristics and Comparison with Respect to Traditional Core-Biopsy 14-16G Systems.Diagnostics (Basel, Switzerland) · 2020Article
- MRI-detected breast lesions: clinical implications and evaluation based on MRI/ultrasonography fusion technology.Japanese journal of radiology · 2019Review
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study is to present a 6-year prospective evaluation of second-look ultrasound (US) using volume navigation (V Nav) for MRI-detected additional breast lesions.
methodsAfter IRB approvals in both institutions, 1930 consecutive prone MRI breast examinations in 1437 patients were prospectively evaluated. All patients with an MRI-detected additional lesion underwent second-look US, and if occult, contrast-enhanced MRI in supine position was performed for US and MRI co-registration. For patients with breast hypertrophy, MRI-guided biopsy was performed directly. Pathologic examination was the standard of reference. One-way ANOVA and chi-square tests were used.
resultsIn 490 MRI examinations (25.4%, 490/1930), at least one additional breast lesion was detected for a total of 722 only MRI-detected lesions. Second-look US identified 549 additional lesions (23 ± 8 mm); 362 (65.9%, 362/549) proved benign at pathology and 187 (34.1%, 187/549) malignant. Second-look US with V Nav identified 151 additional lesions (17 ± 9 mm, p = n.s.); 67 (44.4%, 67/151) proved benign at pathology and 84 (55.6%, 84/151) malignant. MRI-guided biopsy was performed on 22 additional breast lesions (22 ± 8 mm, p = n.s.); pathology revealed 20 (90.9%, 20/22) benign lesions and 2 (9.1%, 2/22) malignant ones. Mass lesions were significantly higher in the second-look US group (p < 0.001). No significant difference in lesion dimension was found between the three groups (p = 0.729).
conclusionsSecond-look US with V Nav can be effective in detecting a large number of additional breast lesions occult at second-look US and to biopsy a significant number of malignant lesions safely and irrespective of distance from skin or lesion position. KEY POINTS: • Second-look US with volume navigation is effective in detecting occult additional lesions. • Permits safe biopsies irrespective of position and depth • Reduces the need for MRI-guided biopsy.
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