Evidence map›Paper›PMID 30324383›Full record

ArticleEuropean radiology2019

Speed of sound ultrasound: a pilot study on a novel technique to identify sarcopenia in seniors.

Sergio J Sanabria, Katharina Martini, Gregor Freystätter, Lisa Ruby, Orcun Goksel, Thomas Frauenfelder, Marga B Rominger

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Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 50 citations in OpenAlex.

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  12. Speed-of-sound imaging using diverging waves.International journal of computer assisted radiology and surgery · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sergio J SanabriaComputer Assisted Applications in Medicine, ETH Zurich, Sternwartstrasse 7, 8092, Zurich, Switzerland.
Katharina MartiniInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Gregor FreystätterDepartment of Geriatrics and Aging Research, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Lisa RubyInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Orcun GokselComputer Assisted Applications in Medicine, ETH Zurich, Sternwartstrasse 7, 8092, Zurich, Switzerland.
Thomas FrauenfelderInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Marga B RomingerInstitute of Diagnostic and Interventional Radiology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. Marga.Rominger@usz.ch.
University Hospital of Zurich · CHETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo measure speed of sound (SoS) with a novel hand-held ultrasound technique as a quantitative indicator for muscle loss and fatty muscular degeneration.

methodsBoth calf muscles of 11 healthy, young females (mean age 29 years), and 10 elderly females (mean age 82 years) were prospectively examined with a standard ultrasound machine. A flat Plexiglas® reflector, on the opposite side of the probe with the calf in between, was used as timing reference for SoS (m/s) and ΔSoS (variation of SoS, m/s). Handgrip strength (kPA), Tegner activity scores, and 5-point comfort score (1 = comfortable to 5 = never again) were also assessed. Ultrasound parameters (muscle/adipose thickness, echo intensity) were measured for comparison.

resultsBoth calves were assessed in less than two minutes. All measurements were successful. The elderly females showed significantly lower SoS (1516 m/s, SD17) compared to the young adults (1545 m/s, SD10; p < 0.01). The ΔSoS of elderly females was significantly higher (12.2 m/s, SD3.6) than for young females (6.4 m/s, SD1.5; p < 0.01). Significant correlations of SoS with hand grip strength (r = 0.644) and Tegner activity score (r

conclusionsThere were significant differences of SoS and ΔSoS between young and elderly females. Measurements were fast and well tolerated. The novel technique shows potential for sarcopenia quantification using a standard ultrasound machine. KEY POINTS: • Speed of sound ultrasound: a novel technique to identify sarcopenia in seniors. • Measurements were fast and well tolerated using a standard ultrasound machine. • The novel technique shows potential for sarcopenia quantification.

Indexed as

AdultAged, 80 and overAnimalsCattleFemaleHand StrengthHumansMaleMuscle, SkeletalPilot ProjectsSarcopeniaUltrasonographyAdipose tissueAgingSarcopeniaSkeletal muscleUltrasonography

Identifiers

PMID30324383
OpenAlexW2897318637

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.