Evidence map›Paper›PMID 30324340›Full record

ArticleHerz2019

Evaluation of myocardial viability in myocardial infarction patients by magnetic resonance perfusion and delayed enhancement imaging.

W Sun, L Sun, F Yang, X Zhao, R Cai, W Yuan

Abstract read
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In one paragraph

Article in Herz, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Analysis of Characteristics of Patients with Non-ST-Segment Elevation Myocardial Infarction by Cardiac Magnetic Resonance Imaging.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

W SunDepartment of Cardiology, Second Affiliated Hospital of Kunming Medical University, 374 Dianmian road, Wuhua Area, 650101, Kunming, China.
L SunDepartment of Cardiology, Second Affiliated Hospital of Kunming Medical University, 374 Dianmian road, Wuhua Area, 650101, Kunming, China. sunlinkm@sina.com.ORCID http://orcid.org/0000-0002-6138-5712
F YangDepartment of Cardiology, Second Affiliated Hospital of Kunming Medical University, 374 Dianmian road, Wuhua Area, 650101, Kunming, China.
X ZhaoDepartment of Radiology, Second Affiliated Hospital of Kunming Medical University, 650101, Kunming, China.
R CaiDepartment of Radiology, Second Affiliated Hospital of Kunming Medical University, 650101, Kunming, China.
W YuanDepartment of Radiology, First Affiliated Hospital of Chengdu Medical College, 610500, Chengdu, China.

Funding

Basic study of 3.0TMRI combined with 256 slice CT on microcirculation and ventricular remodeling in chronic myocardial infarction 81260213
6 · The paper itself

Abstract

objectiveCardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level.

methodsWe performed CMR in 30 myocardial infarction (MI) patients within 7-10 days. At the 6‑month follow-up, CMR was used to evaluate the impact of abnormal reperfusion and observe the transmural extent of infraction on recovery of function.

resultsThe left ventricle was divided into 16 segments using the American Heart Association classification. Infarcts were detected in 202 of the 480 segments (42%) by delayed enhancement magnetic resonance imaging (DE-MRI). According to first-pass myocardial perfusion, abnormal perfusion was detected in 278 of 480 segments (60%), reduced perfusion was identified in 173 of 278 (62%), and perfusion defects in 105 of 278 segments (38%). The results showed that the segments with abnormal perfusion were larger than in DE-MRI (P < 0.05), indicating that the area of abnormal perfusion segments extend significantly beyond the region of infarction. Microvascular perfusion with an infarcted region was lower compared to non-infarcted segments (P < 0.05). The extent of myocardial hyperenhancement correlated inversely with microvascular perfusion (P < 0.05). Segments with severe microvascular perfusion and >75% transmural infarction on the 7‑ to 10-day scan had markedly increased at the 6‑month follow-up (P < 0.01), indicating a lack of recovery of cardiac function.

conclusionsDE-MRI combined with microvascular perfusion may be effective to detect viable myocardium in patients with MI and may provide a means of predicting whether revascularization will be effective.

Indexed as

HeartMagnetic Resonance ImagingMyocardial InfarctionContrast MediaHeart VentriclesHumansMagnetic Resonance SpectroscopyMaleMyocardiumContrast MediaCardiovascular diseaseDelayed enhancement magnetic resonance imagingFirst-pass myocardial perfusionLeft ventricular dysfunctionMyocardial viability

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.