Evidence map›Paper›PMID 30324238›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2019

Higher age is a major driver of in-hospital adverse events independent of comorbid diseases among patients with isolated mild traumatic brain injury.

Barbara R Schmidt, Rudolf M Moos, Dilek Könü-Leblebicioglu, Heike A Bischoff-Ferrari, Hans-Peter Simmen, Hans-Christoph Pape, Valentin Neuhaus

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Outcomes After Traumatic Brain Injury Surgery: Investigating Racial Disparities.Journal of racial and ethnic health disparities · 2026
    Article
  3. Review
  4. Article
  5. Focus on geriatric trauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Barbara R SchmidtDivision of Trauma Surgery, Department of Surgery, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Rudolf M MoosMedical Directorate, University Hospital Zurich, Zurich, Switzerland.
Dilek Könü-LeblebiciogluDepartment of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Heike A Bischoff-FerrariDepartment of Geriatrics, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Hans-Peter SimmenDivision of Trauma Surgery, Department of Surgery, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Hans-Christoph PapeDivision of Trauma Surgery, Department of Surgery, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Valentin NeuhausDivision of Trauma Surgery, Department of Surgery, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland. valentin.neuhaus@gmx.ch.ORCID http://orcid.org/0000-0003-4012-5628
University of Zurich · CHUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goal of this study was to investigate if and to what extent age, independent of comorbid diseases, is a risk factor for negative in-hospital outcome with mTBI.

methodsIn a retrospective cohort study, we identified 1589 adult patients treated for isolated mTBI in our level-1 trauma center between 2008 and 2015. We used logistic regression analyses to assess the odds of any adverse event by age group (< 65, 65-75, 76-85, and 85+), adjusting for gender and chronic diseases.

resultsThe prevalence of any adverse event during in-hospital care among mTBI patients was 3.2% overall, 1.8% among those younger than age 65 years, 2.1% among those age 65-75 years, 8% among those age 75-85 years, and 19% among those age 85+ years. The odds of any adverse event were similar in patients aged 65-75 years, but increased among senior patients 4.4-fold for age 75-85 years (OR 4.4, 95%CI 2.0-9.8, p < 0.001), and 18-fold for age 85+ years (OR 18.0, 95%CI 8.7-37, p < 0.001). Additionally, chronic alcohol abuse (OR 7.0, 95%CI 3.2-15, p < 0.001), diseases of the musculoskeletal system (OR 4.3, 95%CI 1.5-13, p = 0.008), and diabetes mellitus (OR 2.7, 95%CI 1.2-6.5, p = 0.023) increased the odds of any adverse events independent of age and all other covariates.

conclusionsThe odds of sustaining an adverse event increased exponentially after age 75 independent of gender and any comorbid diseases. Our data support international efforts to manage senior patients in interdisciplinary geriatric trauma units.

Indexed as

Hospital MortalityTrauma CentersAgedAged, 80 and overAge FactorsBrain ConcussionFemaleHumansMaleOdds RatioPredictive Value of TestsRetrospective StudiesRisk FactorsAdverse eventsMinor traumatic brain injuryRisk factorsSenior patients

Identifiers

PMID30324238
OpenAlexW2896001125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.