Evidence map›Paper›PMID 30324148›Full record

ArticleClinical and experimental hepatology2018

Hepatitis B virus treatment in hepatocellular carcinoma patients prolongs survival and reduces the risk of cancer recurrence.

Monika Pazgan-Simon, Krzysztof A Simon, Ewa Jarowicz, Katarzyna Rotter, Anna Szymanek-Pasternak, Jolanta Zuwała-Jagiełło

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Clinical and experimental hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Monika Pazgan-SimonDepartment of Infectious Disease 1, Regional Specialistic Hospital, Wroclaw, Poland.
Krzysztof A SimonDepartment of Infectious Disease and Hepatology, Wroclaw Medical University, Wroclaw, Poland.
Ewa JarowiczDepartment of Infectious Disease 2, Regional Specialistic Hospital, Wroclaw, Poland.
Katarzyna RotterDepartment of Infectious Disease 1, Regional Specialistic Hospital, Wroclaw, Poland.
Anna Szymanek-PasternakDepartment of Infectious Disease and Hepatology, Wroclaw Medical University, Wroclaw, Poland.
Jolanta Zuwała-JagiełłoDepartment of Pharmacutical Biochemistry, Wroclaw Medical University, Wroclaw, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis B virus (HBV) infection and HBV-related liver disease are estimated to affect about 240 million people worldwide. Now that a vaccine is available, the number of new HBV infection cases has plummeted. Yet, there are still regions with very high incidence of HBV. Hepatocellular carcinoma (HCC) is the fourth to six most common malignancy in men and the ninth most common malignancy in women worldwide. 54% of all HCC cases are HBV-associated, making it the most common cause of cancer worldwide. Hepatitis B therapy prevents progression of chronic hepatitis to cirrhosis and HCC development, but even with the best HBV treatment, such patients are still at risk of HCC. Also in patients after transarterial chemoembolization (TACE), liver resection (hepatectomy) or liver transplant, suppression of hepatitis B virus (HBV) improves patient survival. In this paper we present current possibilities of HCC and HBV treatment, which lead to improved survival and quality of life.

Indexed as

HBV treatmentHCCHCC treatment

Identifiers

PMID30324148
PMCPMC6185928
OpenAlexW2898074532

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.