Evidence map›Paper›PMID 30324016›Full record

ArticlePeerJ2018

Young, American Indian or Alaskan Native, and born in the USA: at excess risk of starting extra-medical prescription pain reliever use?

Maria A Parker, Catalina Lopez-Quintero, James C Anthony

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Maria A ParkerDepartment of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, United States of America.
Catalina Lopez-QuinteroDepartment of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, United States of America.
James C AnthonyDepartment of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, United States of America.
Michigan State University · USUniversity of Vermont · US

Funding

Training Program in Drug Dependence EpidemiologyT32DA021129 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2006 to 2016
$2.7M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
Drug use disparities among Hispanics: elucidating the complex interactions between socio-cultural, neurocognitive and drug use-related factorsK01DA046715 · NIDA · UNIVERSITY OF FLORIDA · PI LOPEZ-QUINTERO, CATALINA · 2018 to 2022
$763k
NIDA NIH HHS K01 DA046715NIDA NIH HHS K05 DA015799NIDA NIH HHS T32 DA021129
6 · The paper itself

Abstract

backgroundPrescription pain reliever (PPR) overdoses differentially affect 'American Indian/Alaskan Natives' in the United States (US). Here, studying onset of extra-medical PPR use in 12-24-year-olds, we examine subgroup variations in rates of starting to use prescription pain relievers extra-medically (i.e., to get 'high' or for other reasons outside boundaries of prescriber's intent). Risk differences (RD) are estimated for US-born versus non-US-born young people, stratified by American Indian/Alaskan Natives versus other ethnic self-identities.

methodsBetween 2002-2009, nationally representative cross-sectional samples of 12-24-year-old non-institutionalized civilians completed interviews for the US National Surveys of Drug Use and Health. Analysis-weighted annual incidence estimates, RD, and confidence intervals (CI) are from the Restricted-use Data Analysis System, an online software tool for US National Surveys of Drug Use and Health.

resultsEach year, an estimated 2.5% of 12-24-year-olds in the US start using PPR extra-medically (95% CI [2.1%-3.0%]). Estimates for the US-born (3.8%; 95% CI [3.7%-3.9%]) are larger (non-US-born: 1.8%; 95% CI [1.5%-2.0%]; RD = 2.0; DISCUSSION: Each year, one in 20 of US-born American Indian/Alaskan Natives starts using PPR extra-medically. Overdose prevention is important, but is no substitute for primary prevention initiatives for all young people. The observed epidemiological patterns can guide targeted prevention initiatives for the identified higher risk subgroups in complement with more universal prevention efforts intended to reduce incidence of first extra-medical PPR use, a crucial rate-limiting step on the path toward more serious drug involvement (i.e., progressing past initial use).

Indexed as

AdolescentsForeign-bornOpioidsPrescription pain relieversUS-born

Identifiers

PMID30324016
PMCPMC6181070
OpenAlexW2894633635

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.