ArticleTranslational vision science & technology2018
Iris Color and Lens Thickness in Chinese Teenagers.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Assessment of iris pigment epithelium depolarization and associated factors using polarization-sensitive anterior segment optical coherence tomography.International ophthalmology · 2025Article
- Iris surface features and anterior chamber depth in Chinese adolescents.BMC ophthalmology · 2020Article
- Distribution and Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness and Its Association with Sleep Quality in Chinese Teenagers.Journal of ophthalmology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to determine the association of iris color with lens thickness (LT) in a school-based sample of Chinese teenagers.
methodsIn total, 2346 grade 7 students, from 10 middle schools, aged 13 to 14 years in Mojiang located in Southwestern China were included in the analysis. A grading system was developed to assess iris color based on standardized slit-lamp photographs. LT was measured by the LenStar LS900. Refractive error was measured after cycloplegia using an autorefractor and ocular biometric parameters, including axial length (AL), were measured using an IOL Master.
resultsThere was a significant trend of decreasing LTs with darker iris color. On average, eyes with "grade 1" (the lightest) iris color, when compared with those with "grade 5" (the darkest), had greater LTs (mean difference, 0.1 mm). After adjusting for other potential confounders including sex, height, and ALs in generalized estimating equation models, the trend was similar and did not change significantly. Compared with individuals with iris color of grade 1, those with grade 5 had a thinner lens of 0.1 mm (95% confidence interval [CI]: 0.01, 0.19) in sex-adjusted model and a 0.09 mm (95% CI: 0, 0.18) in multivariate-adjusted model.
conclusionsLighter iris color might be associated with greater LTs in Chinese teenagers. The biological mechanisms underlying the association warrant further clarification. TRANSLATIONAL RELEVANCE: As LT is an important refractive component, knowledge on the effect of iris color on LTs may assist in the design of novel technologies, which could control refractive development.
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