Evidence map›Paper›PMID 30323899›Full record

ArticleOncotarget2018

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines.

Moses Koobotse, Jeff Holly, Claire Perks

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Acetyl-CoA Carboxylases and Diseases.Frontiers in oncology · 2022
    Review
  6. BRCA1: An Endocrine and Metabolic Regulator.Frontiers in endocrinology · 2022
    Review
  7. Article
  8. Lipid metabolism and cancer.The Journal of experimental medicine · 2021
    Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Moses KoobotseIGFs and Metabolic Endocrinology Group, Translational Health Sciences, University of Bristol, Bristol, UK.
Jeff HollyIGFs and Metabolic Endocrinology Group, Translational Health Sciences, University of Bristol, Bristol, UK.
Claire PerksIGFs and Metabolic Endocrinology Group, Translational Health Sciences, University of Bristol, Bristol, UK.
University of Bristol · GB

Funding

Cancer Research UK 19169
6 · The paper itself

Abstract

Within populations carrying the same genetic predisposition, the penetrance of

Indexed as

BRCA1cancerIGF-Inon-genomicp-ACCA

Identifiers

PMID30323899
PMCPMC6173354
OpenAlexW2892330346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.