ReviewPlant methods2018
In vitro thermotherapy-based methods for plant virus eradication.
Review in Plant methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04363541 (A Multicenter, Open-label, Parallel-group, Randomized, Adaptive Trial to Evaluate Local Thermotherapy in Patients With Mild-to-moderate COVID-19, to Prevent Disease Progression), which is not on this map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter, Open-label, Parallel-group, Randomized, Adaptive Trial to Evaluate Local Thermotherapy in Patients With Mild-to-moderate COVID-19, to Prevent Disease Progression
Who cites it
37 citing papers in PubMed, 130 citations in OpenAlex.
- Protocol for model-guided alternating high-temperature thermotherapy to eliminate major viruses from diverse sugarcane cultivars.STAR protocols · 2026Article
- Review
- Unraveling Shallot Viral Diversity: PCR Detection and In Vitro Culture.Pathogens (Basel, Switzerland) · 2026Article
- Non-Thermal Plasma Technologies for Plant Virus Inactivation: Sources, Mechanisms, and Practical Applications.The plant pathology journal · 2026Review
- Effects of Hot Water and Plant Growth Regulator Treatments on Bud Germination and Pathogen Elimination in Citrus Scions.Plants (Basel, Switzerland) · 2026Article
- A model-guided alternating high-temperature thermotherapy achieves complete eradication of sugarcane mosaic virus and preserves physiological integrity inFrontiers in plant science · 2026Article
- Virus-induced gene editing free from tissue culture.Nature plants · 2025Review
- Silent invaders: the hidden threat of asymptomatic phytobiomes to forest biosecurity.The New phytologist · 2025Review
- Transmission, Spread, Longevity and Management of Hop Latent Viroid, a Widespread and Destructive Pathogen Affecting Cannabis (Plants (Basel, Switzerland) · 2025Article
- Electrochemical impedance spectroscopy as a micropropagation monitoring tool for plants: A case study of tamarilloiScience · 2025Article
- Production of HSVd- and PPV-free apricot cultivars by in vitro thermotherapy followed by meristem culture.Plant methods · 2025Article
- Optimization of in vitro propagation and virus eradication using meristem culture and thermotherapy in two geranium species Pelargonium X hortorum ('Zonal') and Pelargonium × domesticum ('Regal').BMC plant biology · 2025Article
- Conservation and valorization of Italian potato biodiversity through genotype-by-sequencing (GBS).Frontiers in plant science · 2025Article
- Assessing the efficacy of thermotherapy combined with chemotherapy or cryotherapy for the eradication of grapevine leafroll-associated virus 3.Frontiers in plant science · 2025Article
- Overview on Current Selectable Marker Systems and Novel Marker Free Approaches in Fruit Tree Genetic Engineering.International journal of molecular sciences · 2024Review
- The Elimination of Viroids through In Vitro Thermotherapy and a Meristem Tip Culture from a New Limonime Hybrid (Biotech (Basel (Switzerland)) · 2024Article
- Towards Pathogen-Free Coconut Germplasm Exchange.Plants (Basel, Switzerland) · 2024Review
- Article
- Article
- An Overview of Mycoviral Curing Strategies Used in Evaluating Fungal Host Fitness.Molecular biotechnology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Production of virus-free plants is necessary to control viral diseases, import novel cultivars from other countries, exchange breeding materials between countries or regions and preserve plant germplasm. In vitro techniques represent the most successful approaches for virus eradication. In vitro thermotherapy-based methods, including combining thermotherapy with shoot tip culture, chemotherapy, micrografting or shoot tip cryotherapy, have been successfully established for efficient eradication of various viruses from almost all of the most economically important crops. The present study reviewed recent advances in in vitro thermotherapy-based methods for virus eradication since the twenty-first century. Mechanisms as to why thermotherapy-based methods could efficiently eradicate viruses were discussed. Finally, future prospects were proposed to direct further studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.