Evidence map›Paper›PMID 30323758›Full record

ArticleCase reports in neurology

Does Natalizumab Induce or Aggravate Psoriasis? A Case Study and Review of the Literature.

Sakis Lambrianides, Evgenios Kinnis, Eleni Leonidou, Marios Pantzaris

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Multiple Sclerosis and Autoimmune Comorbidities.Journal of personalized medicine · 2022
    Review
  3. Article
  4. Natalizumab-Induced Pustular Psoriasis of Palms and Soles.Dermatology practical & conceptual · 2022
    Article
  5. Article
  6. Improvement of Comorbid Psoriasis in Patients With MS Treated With Natalizumab.Neurology(R) neuroimmunology & neuroinflammation · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sakis LambrianidesThe Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Evgenios KinnisThe Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Eleni LeonidouThe Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Marios PantzarisThe Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Cyprus Institute of Neurology and Genetics · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a relatively common immune-mediated chronic inflammatory skin disease. It is well known that interferon-beta, a drug used in the management of relapsing-remitting multiple sclerosis, could exacerbate or induce de novo psoriasis. There is limited evidence in the literature based only on case reports that natalizumab could induce or aggravate psoriasis. In this case study, we present a 33-year-old patient who developed plaque psoriasis during natalizumab treatment.

Indexed as

Autoimmune diseaseMultiple sclerosisNatalizumabPsoriasisTh17 cell

Identifiers

PMID30323758
PMCPMC6180259
OpenAlexW2891640415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.